Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that infects 10 million people
worldwide and kills 2 million people every year. The uptake and utilization of nutrients by …

Mast cells (MCs) are particularly abundant at host-environment interfaces, such as skin and
intestinal mucosa. Because of their location, it has been hypothesized that MCs can act as …

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the
various nutrients available during its life cycle. However, in the nutritionally stringent …

The pathogen Salmonella Typhimurium is a common cause of diarrhea and invades the gut
tissue by injecting a cocktail of virulence factors into epithelial cells, triggering actin …

Multi-drug-resistant tuberculosis (TB) is a major public health problem, concerning about
half a million cases each year. Patients hardly adhere to the current strict treatment …

Phagocytosis is necessary for antigen degradation and presentation, the activation of the
adaptive immune response and the elimination of pathogenic micro-organisms. The …

Tuberculosis (TB) is currently the number one killer among infectious diseases worldwide.
Lipids are abundant molecules during the infectious cycle of Mycobacterium tuberculosis …

The cellular plasma membrane serves as a portal for the entry of intracellular pathogens. An
essential step for an intracellular pathogen to gain entry into a host cell therefore is to be …

Mast cells are primarily known for their role in defense against pathogens, particularly
bacteria; neutralization of venom toxins; and for triggering allergic responses and …

Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-
negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome …