High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN-HFS) is the
preferred surgical treatment for advanced Parkinson's disease. In the 15 years since its …

Introduction: Deep brain stimulation is a safe and effective neurointerventional technique for
the treatment of movement disorders. Electrical stimulation of subcortical structures may …

Parkinson's disease (PD) is a common, degenerative disorder of the central nervous system.
Individuals experience predominantly extrapyramidal symptoms including resting tremor …

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidum internus
(GPi) improves motor functions in patients with Parkinson's disease (PD) but may cause a …

Parkinsonism is a progressive motor disease that affects 1.5 million Americans and is the
second most common neurodegenerative disease after Alzheimer's. Typical …

The demonstration that dopamine loss is the key pathological feature of Parkinson's disease
(PD), and the subsequent introduction of levodopa have revolutionalized the field of PD …

Neurostimulation of the subthalamic nucleus (STN) is an established treatment for motor
symptoms in advanced Parkinson disease (PD), although concerns exist regarding the …

Background Subthalamic nucleus (STN) deep brain stimulation (DBS) represents a well-
established treatment for patients with advanced Parkinson's disease (PD) insufficiently …

The benefit of deep brain stimulation (DBS) in controlling the motor symptoms of Parkinson's
disease is well established, however, the impact on the non-motor symptoms (NMS) remains …

Background and objective The extent to which deep brain stimulation (DBS) can improve
quality of life may be perceived as a permanent trade-off between neurological …