Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Current research topics in FAPI theranostics: a bibliometric analysis

AF van den Hoven, RGM Keijsers, MGEH Lam… - European Journal of …, 2023 - Springer
Purpose The study aimed to provide a comprehensive bibliometric overview of the current
scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission …

FAPI PET/CT imaging—an updated review

KR Chandekar, A Prashanth, S Vinjamuri, R Kumar - Diagnostics, 2023 - mdpi.com
Despite revolutionizing the field of oncological imaging, Positron Emission Tomography
(PET) with [18F] Fluorodeoxyglucose (FDG) as its workhorse is limited by a lack of specificity …

Theranostics in targeting fibroblast activation protein bearing cells: progress and challenges

S Rezaei, E Gharapapagh, S Dabiri, P Heidari… - Life Sciences, 2023 - Elsevier
Cancer cells are surrounded by a complex and highly dynamic tumor microenvironment
(TME). Cancer-associated fibroblasts (CAFs), a critical component of TME, contribute to …

Impact of 68Ga-FAPI PET/CT on staging and oncologic management in a cohort of 226 patients with various cancers

SA Koerber, M Röhrich, L Walkenbach… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Since the development of fibroblast activation protein–targeted radiopharmaceuticals, 68Ga-
fibroblast activation protein inhibitor (FAPI) PET/CT has been found to be suitable for …

[68Ga]Ga-FAPI PET for the evaluation of digestive system tumors: systematic review and meta-analysis

D Huang, J Wu, H Zhong, Y Li, Y Han, Y He… - European Journal of …, 2023 - Springer
Purpose Digestive system tumors are a group of tumors with high incidence in the world
nowadays. The assessment of digestive system tumor metastasis by conventional imaging …

68Ga-FAPI PET imaging monitors response to combined TGF-βR inhibition and immunotherapy in metastatic colorectal cancer

K Li, W Liu, H Yu, J Chen, W Tang… - The Journal of …, 2024 - Am Soc Clin Investig
BACKGROUND Improving and predicting tumor response to immunotherapy remains
challenging. Combination therapy with a transforming growth factor-β receptor (TGF-βR) …

FAPI PET/CT in diagnostic and treatment management of colorectal cancer: review of current research status

Z Cheng, S Wang, S Xu, B Du, X Li, Y Li - Journal of Clinical Medicine, 2023 - mdpi.com
FAPI PET/CT is a novel imaging tool targeting fibroblast activation protein (FAP), with high
tumor uptake rate and low background noise. Therefore, the appearance of FAPI PET/CT …

Head-to-head comparison of FDG and radiolabeled FAPI PET: a systematic review of the literature

P Guglielmo, P Alongi, L Baratto, E Abenavoli… - Life, 2023 - mdpi.com
FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging,
which have demonstrated several advantages over [18F] FDG, especially in the case of low …

The superiority of fibroblast activation protein inhibitor (FAPI) PET/CT versus FDG PET/CT in the diagnosis of various malignancies

Y Dong, H Zhou, A Alhaskawi, Z Wang, J Lai, C Yao… - Cancers, 2023 - mdpi.com
Simple Summary Fibroblast activation protein is a newly discovered biomarker in various
tumor types. Using inhibitors ligated with radiopharmaceuticals, nuclear medicine …