Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis

E Thijssen, A Van Caam, PM Van Der Kraan - Rheumatology, 2015 - academic.oup.com
OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …

Ascorbic acid: its role in immune system and chronic inflammation diseases

A Sorice, E Guerriero, F Capone… - Mini reviews in …, 2014 - ingentaconnect.com
Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing
the scurvy disease, and became very popular for its antioxidant properties. It is an important …

Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity

HK Vincent, KE Innes… - Diabetes, obesity and …, 2007 - Wiley Online Library
Purpose: Obesity may be a state of chronic oxidative stress. Oxidative stress may be the
mechanism underlying the development of co‐morbidities in obesity. This review provides a …

Paraoxonase activity in high-density lipoproteins: a comparison between healthy and obese females

G Ferretti, T Bacchetti, C Moroni… - The journal of …, 2005 - academic.oup.com
Paraoxonase, an enzyme associated with high-density lipoprotein (HDL-PON), exerts a
protective effect against oxidative damage of circulating cells and lipoproteins, modulates …

Paraoxonase-1 as a regulator of glucose and lipid homeostasis: impact on the onset and progression of metabolic disorders

MJ Meneses, R Silvestre, I Sousa-Lima… - International journal of …, 2019 - mdpi.com
Metabolic disorders are characterized by an overall state of inflammation and oxidative
stress, which highlight the importance of a functional antioxidant system and normal activity …

Peroxyl radicals: inductors of neurodegenerative and other inflammatory diseases. Their origin and how they transform cholesterol, phospholipids, plasmalogens …

G Spiteller - Free Radical Biology and Medicine, 2006 - Elsevier
The most oxygen-sensitive constituents of cells are polyunsaturated fatty acids (PUFAs),
which are incorporated in the outermost layer of cells in the form of phospholipids. PUFAs …

Inflammatory pathways linking obesity and ovarian dysfunction

RL Robker, LLY Wu, X Yang - Journal of reproductive immunology, 2011 - Elsevier
This review summarizes some of the recent advances in obesity research and describes
how we and others have built upon these findings to better understand the impact of obesity …

Oxidative stress in normal‐weight obese syndrome

L Di Renzo, F Galvano, C Orlandi, A Bianchi… - …, 2010 - Wiley Online Library
The normal‐weight obese (NWO) syndrome was identified in women whose body weight
(BW) and BMI are normal but whose fat mass (FM) is> 30%. In these subjects, an early …

Vitamin C in the treatment and/or prevention of obesity

DF Garcia-Diaz, P Lopez-Legarrea… - Journal of nutritional …, 2014 - jstage.jst.go.jp
Obesity has emerged as one of the major health threats worldwide. Moreover, an excessive
body fat accumulation, which defines this disease, could lead to several associated clinical …

[HTML][HTML] Circulating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women

T Weinbrenner, H Schröder, V Escurriol, M Fito… - The American journal of …, 2006 - Elsevier
Background: Obesity is associated with oxidative stress, and the oxidation of LDL is thought
to play a crucial role in the generation of atherosclerotic lesions. Objective: The objective …