Nitric oxide (NO) is a short-lived, diatomic, lipophilic gas that plays an integral role in
defending against pathogens. Among its many functions are involvement in immune cell …

Nitric oxide synthases are the major sources of nitric oxide, a critical signaling molecule
involved in a wide range of cellular and physiological processes. These enzymes comprise …

Nitric oxide (NO) signaling regulates various physiological processes in both animals and
plants. In animals, NO synthesis is mainly catalyzed by NO synthase (NOS) enzymes …

Nitric oxide (NO) is produced by enzymatic activity of neuronal (nNOS), endothelial (eNOS),
and inducible nitric oxide synthase (iNOS) and modulates a broad spectrum of physiological …

Atherosclerosis is one of the key problems of modern medicine, which is due to the high
prevalence of atherosclerotic cardiovascular diseases and their significant share in the …

Aquatic environments exhibit wide temporal and spatial variations in oxygen levels
compared to terrestrial environments. Fish are an excellent model for elucidating the …

Nitric oxide (NO) is a key signaling molecule in almost all organisms and is active in a
variety of physiological and pathological processes. Our understanding of the peculiarities …

NADPH–cytochrome P450 oxidoreductase (CYPOR) and nitric oxide synthase (NOS), two
members of the diflavin oxidoreductase family, are multi-domain enzymes containing distinct …

All animals evolved from a single lineage of unicellular precursors more than 600 million
years ago. Thus, the biological and genetic foundations for animal sensation, cognition and …

The study of the evolutionary origin of vertebrates has been linked to the study of genome
duplications since Susumo Ohno suggested that the successful diversification of vertebrate …