[HTML][HTML] Biocatalysis

EL Bell, W Finnigan, SP France, AP Green… - Nature Reviews …, 2021 - nature.com
Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …

Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods

S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

Biocatalysis making waves in organic chemistry

U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

Engineered cytochrome P450 for direct arylalkene-to-ketone oxidation via highly reactive carbocation intermediates

S Gergel, J Soler, A Klein, KH Schülke, B Hauer… - Nature Catalysis, 2023 - nature.com
Ketones are crucial intermediates in synthesis and frequent moieties in many products. The
direct regioselective synthesis of ketones from internal alkenes could simplify synthetic …

Enantioselective Transformations in the Synthesis of Therapeutic Agents

H Yang, H Yu, IA Stolarzewicz, W Tang - Chemical Reviews, 2023 - ACS Publications
The proportion of approved chiral drugs and drug candidates under medical studies has
surged dramatically over the past two decades. As a consequence, the efficient synthesis of …

Enzymatic asymmetric synthesis of chiral amino acids

YP Xue, CH Cao, YG Zheng - Chemical Society Reviews, 2018 - pubs.rsc.org
Chiral amino acids are extensively applied in the pharmaceutical, food, cosmetic,
agricultural, and feedstuff industries. The development of synthetic methodologies for …

New generation of biocatalysts for organic synthesis

BM Nestl, SC Hammer, BA Nebel… - Angewandte Chemie …, 2014 - Wiley Online Library
The use of enzymes as catalysts for the preparation of novel compounds has received
steadily increasing attention over the past few years. High demands are placed on the …

A retrosynthesis approach for biocatalysis in organic synthesis

ROMA de Souza, LSM Miranda… - … –A European Journal, 2017 - Wiley Online Library
For the planning of an organic synthesis route, the disconnection approach guided by
retrosynthetic analysis of possible intermediates and the chemical reactions involved, back …

Homogeneous catalysis for the production of low-volume, high-value chemicals from biomass

TA Bender, JA Dabrowski, MR Gagné - Nature Reviews Chemistry, 2018 - nature.com
The transition from petroleum to biorenewable sources of carbon to meet our energy and
chemical feedstock needs is difficult, in part because these sources are so different, with …