Lipid nanoparticle (LNP) enables mRNA delivery for cancer therapy

Y Zong, Y Lin, T Wei, Q Cheng - Advanced Materials, 2023 - Wiley Online Library
Messenger RNA (mRNA) has received great attention in the prevention and treatment of
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …

Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles

J Wang, M Zhu, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …

Hyaluronic acid-based nanocarriers for anticancer drug delivery

CP Fu, XY Cai, SL Chen, HW Yu, Y Fang, XC Feng… - Polymers, 2023 - mdpi.com
Hyaluronic acid (HA), a main component of the extracellular matrix, is widely utilized to
deliver anticancer drugs due to its biocompatibility, biodegradability, non-toxicity, non …

[HTML][HTML] Nanovaccines: a game changing approach in the fight against infectious diseases

MAH Abusalah, H Chopra, A Sharma… - Biomedicine & …, 2023 - Elsevier
The field of nanotechnology has revolutionised global attempts to prevent, treat, and
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …

Regulation of nanoliposome rigidity and bioavailability of oligomeric proanthocyanidin with phytosterols containing different C3 branches

G Liu, P Sun, J Yan, P Shao, S Feng - ACS Applied Materials & …, 2023 - ACS Publications
The rigidity of nanoliposomes significantly influences their physical stability and in vitro and
in vivo behaviors (eg, cellular uptake, blood circulation, biodistribution, etc.). This study …

Organic–inorganic nanoflowers: from design strategy to biomedical applications

Y Liu, X Ji, Z He - Nanoscale, 2019 - pubs.rsc.org
Organic–inorganic hybrid nanoflowers (NF) with sizes or features on a nanoscale are a
class of flower-shaped nanomaterials self-assembled from metal ions and organic …

Inhibiting mtDNA‐STING‐NLRP3/IL‐1β axis‐mediated neutrophil infiltration protects neurons in Alzheimer's disease

X Xia, X He, T Zhao, J Yang, Z Bi, Q Fu, J Liu… - Cell …, 2024 - Wiley Online Library
Neutrophil is a pathophysiological character in Alzheimer's disease. The pathogen for
neutrophil activation in cerebral tissue is the accumulated amyloid protein. In our present …

Lipid-based drug delivery nanoplatforms for colorectal cancer therapy

C Yang, D Merlin - Nanomaterials, 2020 - mdpi.com
Colorectal cancer (CRC) is a prevalent disease worldwide, and patients at late stages of
CRC often suffer from a high mortality rate after surgery. Adjuvant chemotherapeutics (ACs) …

Advances in biomaterials for the treatment of retinoblastoma

W Farhat, V Yeung, A Ross, F Kahale, N Boychev… - Biomaterials …, 2022 - pubs.rsc.org
Retinoblastoma is the most common primary intraocular malignancy in children. Although
traditional chemotherapy has shown some success in retinoblastoma management, there …

[HTML][HTML] Sodium alginate coating simultaneously increases the biosafety and immunotherapeutic activity of the cationic mRNA nanovaccine

X Duan, Y Zhang, M Guo, N Fan, K Chen, S Qin… - … Pharmaceutica Sinica B, 2023 - Elsevier
The extraordinary advantages associated with mRNA vaccines, including their high
efficiency, relatively low severity of side effects, and ease of manufacture, have enabled …