Fetal lower urinary tract obstruction (LUTO) is associated with high mortality and postnatal
morbidity caused by lung hypoplasia and impaired kidney function. Specific diagnostic …

Objective To establish maternal complication rates for fetoscopic or open fetal surgery.
Methods We conducted a systematic literature review for studies of fetoscopic or open fetal …

Background Congenital infection with human cytomegalovirus is a major cause of morbidity
and mortality. A randomized controlled trial showed that high-dosage valacyclovir prevents …

Objective To evaluate the efficacy of fetal intervention using fetal cystoscopy or
vesicoamniotic shunting in the treatment of severe lower urinary obstruction (LUTO) …

Development of the urogenital system in humans is a complex process; consequently, renal
anomalies are among the most common congenital anomalies. The fetal urinary tract can be …

Objective To evaluate the effect on perinatal and postnatal survival of vesicoamniotic shunt
(VAS) as treatment for fetal lower urinary tract obstruction (LUTO). Methods An electronic …

Fetal megacystis is variably defined and understood. The literature on fetal megacystis was
systematically reviewed, focusing on prenatal diagnosis, associations and outcomes. This …

Objective To present a single center experience of a standardized prenatal multidisciplinary
management protocol for fetal lower urinary tract obstruction (LUTO) and to propose a …

The widespread use of routine second-trimester ultrasounds has increased the detection of
congenital anomalies. One of the most frequently detected abnormalities is the dilation of the …

Posterior urethral valves (PUV) are the most common form of lower urinary tract obstructions
(LUTO). The valves can be surgically corrected postnatally; however, the impairment of …