Overview of pancreatic cancer epidemiology in europe and recommendations for screening in high-risk populations

O Partyka, M Pajewska, D Kwaśniewska, A Czerw… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer is becoming a growing health problem. Its share in the
proportion of neoplasms is increasing. Due to its asymptomatic course, this cancer is often …

Early diagnosis of pancreatic cancer: clinical premonitions, timely precursor detection and increased curative-intent surgery

K Søreide, W Ismail, M Roalsø, J Ghotbi… - Cancer …, 2023 - journals.sagepub.com
Background The overall poor prognosis in pancreatic cancer is related to late clinical
detection. Early diagnosis remains a considerable challenge in pancreatic cancer …

Advances in research on malignant tumors and targeted agents for TOP2A

T Zhou, Y Niu, Y Li - Molecular Medicine Reports, 2024 - spandidos-publications.com
The DNA topoisomerase isoform topoisomerase IIα (TOP2A) is essential for the
condensation and segregation of cellular mitotic chromosomes and the structural …

[HTML][HTML] Advancements in Early Detection and Screening Strategies for Pancreatic Cancer: From Genetic Susceptibility to Novel Biomarkers

Y Shah, DS Dahiya, A Tiwari, H Kumar… - Journal of clinical …, 2024 - mdpi.com
Pancreatic cancer is a rare but lethal cancer due to its biologically aggressive nature,
advanced stage at the time of diagnosis, and poor response to oncologic therapies. The risk …

MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances

GAD Metcalf - Oncogene, 2024 - nature.com
This review explores the topic of microRNAs (miRNAs) for improved early detection of
imperceptible cancers, with potential to advance precision medicine and improve patient …

Economic evaluations of pancreatic cancer screening: a systematic review protocol

R Wittram, HH König, C Brettschneider - BMJ open, 2024 - bmjopen.bmj.com
Introduction The early detection of pancreatic cancer is an important step in reducing
mortality by offering patients curative treatment. Screening strategies in risk populations and …

GI cancer mortality in participants in low dose CT screening for lung cancer with a focus on pancreatic cancer

L Gros, R Yip, Y Zhu, P Li, N Paksashvili, Q Sun… - Scientific Reports, 2024 - nature.com
Lung cancer, the leading cause of cancer deaths globally, has better survival rates with early
detection. Annual low-dose CT (LDCT) screenings are recommended for high-risk …

[HTML][HTML] Informatics strategies for early detection and risk mitigation in pancreatic cancer patients

D Jin, NU Khan, W Gu, H Lei, A Goel, T Chen - Neoplasia, 2025 - Elsevier
This review provides a comprehensive overview of the current landscape in pancreatic
cancer (PC) screening, diagnosis, and early detection. This emphasizes the need for …

[PDF][PDF] Informatics strategies for early detection and risk mitigation in pancreatic cancer patients

A Goel, T Chen - Neoplasia, 2025 - researchgate.net
This review provides a comprehensive overview of the current landscape in pancreatic
cancer (PC) screening, diagnosis, and early detection. This emphasizes the need for …

Cancer Screening: Present Recommendations, the Development of Multi-Cancer Early Development Tests, and the Prospect of Universal Cancer Screening

LN Galeș, MA Păun, RM Anghel, OG Trifănescu - Cancers, 2024 - mdpi.com
Simple Summary This article is intended to serve as a roadmap for scientists, steering them
toward fruitful avenues of investigation. Moreover, the review makes a compelling argument …