Stromal cell-derived factor-1 (CXCL12) and its role in bone and muscle biology

W Gilbert, R Bragg, AM Elmansi, ME McGee-Lawrence… - Cytokine, 2019 - Elsevier
Musculoskeletal disorders are the leading cause of disability worldwide; two of the most
prevalent of which are osteoporosis and sarcopenia. Each affect millions in the aging …

The role of MSCs and cell fusion in tissue regeneration

J Dörnen, T Dittmar - International Journal of Molecular Sciences, 2021 - mdpi.com
Regenerative medicine is concerned with the investigation of therapeutic agents that can be
used to promote the process of regeneration after injury or in different diseases …

Hypoxia preconditioned bone marrow-derived mesenchymal stromal/stem cells enhance myoblast fusion and skeletal muscle regeneration

K Archacka, I Grabowska, B Mierzejewski… - Stem Cell Research & …, 2021 - Springer
Background The skeletal muscle reconstruction occurs thanks to unipotent stem cells, ie,
satellite cells. The satellite cells remain quiescent and localized between myofiber …

SDF-1 and NOTCH signaling in myogenic cell differentiation: the role of miRNA10a, 425, and 5100

B Mierzejewski, I Grabowska, Z Michalska… - Stem Cell Research & …, 2023 - Springer
Background Skeletal muscle regeneration is a complex process regulated by many
cytokines and growth factors. Among the important signaling pathways regulating the …

Influence of media composition on the level of bovine satellite cell proliferation

K Zygmunt, A Otwinowska-Mindur, K Piórkowska… - Animals, 2023 - mdpi.com
Simple Summary Culturing of muscle precursor cells—satellite cells—is the basis for
research on obtaining meat using in vitro techniques, which can become an alternative to …

Comparative study on bone marrow-versus adipose-derived stem cells on regeneration and re-innervation of skeletal muscle injury in Wistar rats

MH Moussa, GG Hamam, AE Abd Elaziz… - Tissue Engineering and …, 2020 - Springer
Background: Skeletal muscle injuries are frequent clinical challenges due to associated
fibrosis and disability. Regenerative medicine is an emerging promising strategy for such …

Young bone marrow transplantation prevents aging‐related muscle atrophy in a senescence‐accelerated mouse prone 10 model

A Inoue, L Piao, X Yue, Z Huang, L Hu… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Young bone marrow transplantation (YBMT) has been shown to stimulate
vascular regeneration in pathological conditions, including ageing. Here, we investigated …

Generating human skeletal myoblast spheroids for vascular myogenic tissue engineering

M Minne, L Terrie, R Wüst, S Hasevoets… - …, 2024 - iopscience.iop.org
Engineered myogenic microtissues derived from human skeletal myoblasts offer unique
opportunities for varying skeletal muscle tissue engineering applications, such as in vitro …

The factors present in regenerating muscles impact bone marrow-derived mesenchymal stromal/stem cell fusion with myoblasts

P Kasprzycka, K Archacka, K Kowalski… - Stem cell research & …, 2019 - Springer
Background Satellite cells, a population of unipotent stem cells attached to muscle fibers,
determine the excellent regenerative capability of injured skeletal muscles. Myogenic …

The miR151 and miR5100 transfected bone marrow stromal cells increase myoblast fusion in IGFBP2 dependent manner

B Mierzejewski, Z Michalska, D Jackowski… - Stem cell reviews and …, 2022 - Springer
Background Bone marrow stromal cells (BMSCs) form a perivascular cell population in the
bone marrow. These cells do not present naïve myogenic potential. However, their …