New insights into the structure and function of class B1 GPCRs
G protein–coupled receptors (GPCRs) are the largest family of cell surface receptors. Class
B1 GPCRs constitute a subfamily of 15 receptors that characteristically contain large …
B1 GPCRs constitute a subfamily of 15 receptors that characteristically contain large …
Prolonged signaling of backbone-modified glucagon-like peptide-1 analogues with diverse receptor trafficking
BP Cary, MV Hager, RK Morris, MJ Belousoff… - bioRxiv, 2024 - biorxiv.org
Signal duration and subcellular location are emerging as important facets of G protein-
coupled receptor (GPCR) function. The glucagon-like peptide-1 receptor (GLP-1R), a …
coupled receptor (GPCR) function. The glucagon-like peptide-1 receptor (GLP-1R), a …