Selenium (Se)-containing compounds have attracted a growing interest as anticancer
agents over recent decades, with mounting reports demonstrating their high efficacy and …

There is an urgent need to develop safer and more effective modalities for the treatment of a
wide range of pathologies due to the increasing rates of drug resistance, undesired side …

Long-term exposure to high levels of arsenic has been documented to induce skin and liver
damage, affecting hundreds of millions of people. While arsenic-induced skin and liver …

Few studies have investigated the association between essential trace elements and
oxidative stress in environmental media and populations with endemic arsenism caused by …

Considering a novel series of zidovudine (AZT) derivatives encompassing selenoaryl
moieties promising candidates as therapeutics, we examined the toxicities elicited by AZT …

Introduction The incorporation of selenium in the structure of nucleosides is a promising
strategy to develop novel therapeutic molecules. Objective To assess the toxic effects of …

Active support for the importance of selenium (Se) in the cell physiology of mammals was
provided in 1973. Two groups of investigators identified Se as part of the enzyme …

Микроэлемент селен, открытый Берцелиусом ещё в 1817 году, на сегодняшний день
остается до конца не познанным и не перестает удивлять многообразием своих …

The disease cancer involves multiple cellular and molecular changes, which converts a
normal cell into a malignant one. Reactive oxygen species acts as the physiological redox …

A zidovudina (AZT), um análogo do nucleosídeo timidina, é amplamente usado nos
esquemas antirretrovirais e mais recentemente foi indicado, em associação com outros …