Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …

Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …

Studies into the mechanisms in resolution of self-limited inflammation and acute reperfusion
injury have uncovered a new genus of pro-resolving lipid mediators coined specialized pro …

Mounting of the acute inflammatory response is crucial for host defense and pivotal to the
development of chronic inflammation, fibrosis, or abscess formation versus the protective …

Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and are
commonly used in the nutritional therapy of cancer patients due to their ample biological …

Background: Emotional disorders are common comorbid affectations that exacerbate the
severity and persistence of chronic pain. Specifically, depressive symptoms can lead to an …

Objective To determine whether dietary interventions that increase n-3 fatty acids with and
without reduction in n-6 linoleic acid can alter circulating lipid mediators implicated in …

Endogenous mechanisms that orchestrate resolution of acute inflammation are essential in
host defense and the return to homeostasis. Resolvin (Rv) D2 is a potent immunoresolvent …

Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Inflammation has been identified as one of the main pathophysiological mechanisms
underlying neuropsychiatric and neurodegenerative disorders. Despite the role of …