Application of plant viruses in biotechnology, medicine, and human health

S Venkataraman, K Hefferon - Viruses, 2021 - mdpi.com
Plant-based nanotechnology programs using virus-like particles (VLPs) and virus
nanoparticles (VNPs) are emerging platforms that are increasingly used for a variety of …

Plant-made vaccines against viral diseases in humans and farm animals

H Su, A Van Eerde, E Rimstad, R Bock… - Frontiers in plant …, 2023 - frontiersin.org
Plants provide not only food and feed, but also herbal medicines and various raw materials
for industry. Moreover, plants can be green factories producing high value bioproducts such …

The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signaling through two downstream effectors

BI Je, F Xu, Q Wu, L Liu, R Meeley, JP Gallagher… - Elife, 2018 - elifesciences.org
Meristems contain groups of indeterminate stem cells, which are maintained by a feedback
loop between CLAVATA (CLV) and WUSCHEL (WUS) signaling. CLV signaling involves the …

Multiple PPR protein interactions are involved in the RNA editing system in Arabidopsis mitochondria and plastids

N Andrés-Colás, Q Zhu, M Takenaka… - Proceedings of the …, 2017 - National Acad Sciences
Recent identification of several different types of RNA editing factors in plant organelles
suggests complex RNA editosomes within which each factor has a different task. However …

Combating human viral diseases: will plant-based vaccines be the answer?

S Venkataraman, K Hefferon, A Makhzoum… - Vaccines, 2021 - mdpi.com
Molecular pharming or the technology of application of plants and plant cell culture to
manufacture high-value recombinant proteins has progressed a long way over the last three …

Plant virus expression vectors: a powerhouse for global health

K Hefferon - Biomedicines, 2017 - mdpi.com
Plant-made biopharmaceuticals have long been considered a promising technology for
providing inexpensive and efficacious medicines for developing countries, as well as for …

Role of heterotrimeric Gα proteins in maize development and enhancement of agronomic traits

Q Wu, M Regan, H Furukawa, D Jackson - PLoS genetics, 2018 - journals.plos.org
Plant shoot systems derive from the shoot apical meristems (SAMs), pools of stems cells that
are regulated by a feedback between the WUSCHEL (WUS) homeobox protein and …

Producing vaccines against enveloped viruses in plants: Making the impossible, difficult

H Peyret, JFC Steele, JW Jung, EC Thuenemann… - Vaccines, 2021 - mdpi.com
The past 30 years have seen the growth of plant molecular farming as an approach to the
production of recombinant proteins for pharmaceutical and biotechnological uses. Much of …

Plant-based vaccines in combat against coronavirus diseases

B Ortega-Berlanga, T Pniewski - Vaccines, 2022 - mdpi.com
Coronavirus (CoV) diseases, including Middle East Respiratory Syndrome (MERS) and
Severe Acute Respiratory Syndrome (SARS) have gained in importance worldwide …

Challenges and prospects of plant-derived oral vaccines against hepatitis b and c viruses

AMM Pantazica, LM Cucos, C Stavaru, JL Clarke… - Plants, 2021 - mdpi.com
Hepatitis B and C viruses chronically affect approximately 3.5% of the global population,
causing more than 800,000 deaths yearly due to severe liver pathogenesis. Current HBV …