Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

In recent years, many studies have focused their attention on the dog as a proper animal
model for human cancer. In dogs, mammary tumors develop spontaneously, involving a …

A high‐fat diet (HFD) leads to long‐term exposure to gut microbial metabolite secondary bile
acids, such as deoxycholic acid (DCA), in the intestine, which is closely linked to colorectal …

The abnormal blood vessels in tumor sites, causing poor tumor perfusion and hypoxia
environment, restrict the chemodynamic therapy (CDT) potency significantly. To attain the …

Glioma is the most common form of primary central nervous malignant tumors. Vasculogenic
mimicry (VM) is a blood supply channel that is different from endothelial blood vessels in …

Glioblastoma (GBM) is a primary tumor in the intracranial compartment. Vasculogenic
mimicry (VM) is a process in which a pipeline of tumor cells that provide blood support to …

Sorafenib is a multi-kinase small molecule inhibitor that targets serine/threonine and
tyrosine kinases including the RAF kinase family, VEGFR-2, and PDGFR. The aim of this …

Human inflammatory breast cancer (IBC) and canine inflammatory mammary cancer (IMC)
are the most aggressive and lethal types of mammary tumors with specific characteristics …

Simple Summary Mammary gland tumors are most frequent in non-castrated female dogs
and represent an interesting model for understanding tumor biology of human breast cancer …

A particular type of tumor that is frequently detected in female dogs who are sexually active
is a mammary tumor. Neoplasia results from DNA-based alterations in cell cycle regulating …