The microgravity environment experienced during spaceflight severely impaired immune
system, making astronauts vulnerable to various diseases that seriously threaten the health …

All terrestrial organisms have evolved and adapted to thrive under Earth's gravitational force.
Due to the increase of crewed space flights in recent years, it is vital to understand how the …

Spaceflight-associated immune system weakening ultimately limits the ability of humans to
expand their presence beyond the earth's orbit. A mechanistic study of microgravity …

The effects of a microgravity environment on the myriad types of immune cells present within
the human body have been assessed both by bench-scale simulation and suborbital …

The in vivo function of p38 mitogen-activated protein kinase (MAPK) signaling in regulating
the response to simulated microgravity is still largely unclear. Using Caenorhabditis elegans …

In the process of exploring space, the astronaut's body undergoes a series of physiological
changes. At the level of cellular behavior, microgravity causes significant alterations …

Ulcerative colitis is an inflammatory disease of the intestine caused by many reasons, and it
may even develop into colon cancer. Probiotics are normal bacteria that exist in the human …

Spaceflight exerts an extreme and unique influence on human physiology as astronauts are
subjected to long-term or short-term exposure to microgravity. During spaceflight, a multitude …

Abstract Space is a hostile environment characterized by high vacuum, extreme
temperatures, meteoroids, space debris, ionospheric plasma, microgravity and space …

As we explore other planetary bodies, astronauts will face unique environmental and
physiological challenges. The human immune system has evolved under Earth's …