Corneal cross-linking (CXL) has profoundly changed the management of keratoconus and
other ectatic corneal diseases. Introduced in the late 1990s, CXL marked the first effective …

Autofluorophores are endogenous fluorescent compounds that naturally occur in the intra
and extracellular spaces of all tissues and organs. Most have vital biological functions–like …

We demonstrate the ability of nondestructive optical imaging techniques such as second-
harmonic generation (SHG), two-photon fluorescence (TPF), fluorescence lifetime imaging …

Myopia and keratoconus have become common corneal diseases that threaten the quality of
human vision, and keratoconus is one of the most common indications for corneal …

Corneal crosslinking (CXL) is a widely applied technique to halt the progression of ectatic
diseases through increasing the thickness and mechanical stiffness of the cornea. This study …

Stiffness-related eye diseases such as keratoconus require comprehensive visualization of
the complex morphological matrix changes. The aim of this study was to use three …

In this paper, a Second-Harmonic-Generation (SHG) microscope was used to study the
relationship between collagen structural arrangement, image quality and polarization …

Two-photon imaging (TPI) microscopy, namely, two-photon excited fluorescence (TPEF),
fluorescence lifetime imaging (FLIM), and second-harmonic generation (SHG) modalities …

Corneal collagen cross-linking is an established procedure for the treatment of certain eye
diseases which is applied to enhance the mechanical stability of such biotissue without …

The properties and structure of the crystalline lens change as time after death passes. Some
experiments have suggested that these might be used to estimate the postmortem interval …