Multistage-responsive clustered nanosystem to improve tumor accumulation and penetration for photothermal/enhanced radiation synergistic therapy

S Hua, J He, F Zhang, J Yu, W Zhang, L Gao, Y Li… - Biomaterials, 2021 - Elsevier
Developing new strategies to overcome biological barriers and achieve efficient delivery of
therapeutic nanoparticles (NPs) is the key to achieve positive therapeutic outcomes in …

A CO2-Responsive Imidazole-Functionalized Fluorescent Material Mediates Cancer Chemotherapy

VTT Ngan, PY Chiou, FB Ilhami, EA Bayle, YT Shieh… - Pharmaceutics, 2023 - mdpi.com
We present a breakthrough in the synthesis and development of functional gas-responsive
materials as highly potent anticancer agents suitable for applications in cancer treatment …

GUMBOS and nanoGUMBOS in chemical and biological analysis: A review

AMO Azevedo, JLM Santos, IM Warner… - Analytica Chimica …, 2020 - Elsevier
GUMBOS (group of uniform materials based on organic salts) is a novel class of materials
that exhibits similar features to those of ionic liquids, but have melting points between 25 …

Recent Progress in Synthesis and Applications of Tunable Materials and Nanomaterials Based on Organic Salts

P Kaur, HK Chopra - ChemistrySelect, 2020 - Wiley Online Library
GUMBOS (group of uniform materials based on organic salts) are a new class of solid
organic ionic materials that shared similar properties as that of ionic liquids, but have a wider …

Interrogating the Role of Endocytosis Pathway and Organelle Trafficking for Doxorubicin-Based Combination Ionic Nanomedicines

M Bashiru, M Rayaan, N Ali, SV Jenkins… - ACS applied bio …, 2024 - ACS Publications
We have studied the endocytic mechanisms that determine subcellular localization for three
carrier-free chemotherapeutic-photothermal (chemo-PTT) combination ionic nanomedicines …

Porphyrin–ferrocene conjugates for photodynamic and chemodynamic therapy

Z Lei, X Zhang, X Zheng, S Liu, Z Xie - Organic & biomolecular …, 2018 - pubs.rsc.org
Chemodynamic therapy can convert endogenous hydrogen peroxide (H2O2) at tumor
localization into the toxic hydroxyl radical (˙ OH) destroying tumor cells. Photodynamic …

Ionic aggregation-induced emission dye with bulky counterions for preparation of bright near-infrared polymeric nanoparticles

N Adarsh, AS Klymchenko - Nanoscale, 2019 - pubs.rsc.org
Dyes exhibiting aggregation-induced emission (AIE) are attractive building blocks for the
preparation of bright fluorescent nanomaterials. AIEgens are especially efficient in pure dye …

Complementary nucleobase interactions drive co-assembly of drugs and nanocarriers for selective cancer chemotherapy

FB Ilhami, EA Bayle, CC Cheng - Pharmaceutics, 2021 - mdpi.com
A new concept in cooperative adenine–uracil (A–U) hydrogen bonding interactions between
anticancer drugs and nanocarrier complexes was successfully demonstrated by invoking the …

Enhanced extraction of methylene blue by dodecyl-methyl imidazolium dodecyl sulfate GUMBOS-magnetic alginate beads

T Bakare-Abidola, WJA Russell, K Jorgensen… - Chemosphere, 2025 - Elsevier
In this study, dodecyl-methyl imidazolium dodecyl sulfonate ([C 12 MIm][DS]) GUMBOS were
synthesized and incorporated into alginate with γ-Fe 2 O 3 to fabricate magnetic adsorbent …

[HTML][HTML] CO2-Responsive adenine nucleobase: New insight into manipulating the photophysical properties and biological activities of functional fluorescent molecules

EA Bayle, TH Su, CW Chiu, CC Cheng - Journal of CO2 Utilization, 2024 - Elsevier
We report important progress in the preparation and development of gas-responsive
fluorescent materials with potential as efficient anticancer treatments and fluorescent probes …