[HTML][HTML] Brain stars take the lead during critical periods of early postnatal brain development: relevance of astrocytes in health and mental disorders

E Vivi, B Di Benedetto - Molecular Psychiatry, 2024 - nature.com
In the brain, astrocytes regulate shape and functions of the synaptic and vascular
compartments through a variety of released factors and membrane-bound proteins. An …

Glycan-specific molecularly imprinted polymers towards cancer diagnostics: merits, applications, and future perspectives

P Li, Z Liu - Chemical Society Reviews, 2024 - pubs.rsc.org
Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …

CTD tetramers: a new online tool that computationally links curated chemicals, genes, phenotypes, and diseases to inform molecular mechanisms for environmental …

AP Davis, TC Wiegers, J Wiegers, B Wyatt… - Toxicological …, 2023 - academic.oup.com
The molecular mechanisms connecting environmental exposures to adverse endpoints are
often unknown, reflecting knowledge gaps. At the Comparative Toxicogenomics Database …

Shaping immunity: The influence of natural selection on population immune diversity

HE Randolph, KA Aracena, YL Lin, Z Mu… - Immunological …, 2024 - Wiley Online Library
Humans exhibit considerable variability in their immune responses to the same immune
challenges. Such variation is widespread and affects individual and population‐level …

Genotype× environment interactions in gene regulation and complex traits

C Boye, S Nirmalan, A Ranjbaran, F Luca - Nature Genetics, 2024 - nature.com
Genotype× environment interactions (GxE) have long been recognized as a key mechanism
underlying human phenotypic variation. Technological developments over the past 15 years …

Gene–environment interactions in human health

E Herrera-Luis, K Benke, H Volk… - Nature Reviews …, 2024 - nature.com
Gene–environment interactions (G× E), the interplay of genetic variation with environmental
factors, have a pivotal impact on human complex traits and diseases. Statistically, G× E can …

Artificial Breakthrough of Cell Membrane Barrier for Transmembrane Substance Exchange: A Review of Recent Progress

L Wang, X Zhu, C Xu, D Jin, X Ma - Advanced Functional …, 2024 - Wiley Online Library
Cell membrane composed of lipid bilayer is a selectively permeable membrane that only
allows specific molecules to pass through. While such selectivity is essential for the survival …

Flow injection analysis coupled with photoelectrochemical immunoassay for simultaneous detection of anti-SARS-CoV-2-spike and anti-SARS-CoV-2-nucleocapsid …

R Wang, S Wang, W Guo, T Zhang, Q Kang… - Analytica Chimica …, 2023 - Elsevier
A thin-layer flow cell of low internal volume (12 μL) is incorporated in a flow injection
analysis (FIA) system for simultaneous and real-time photoelectrochemical (PEC) …

[HTML][HTML] Integration of epigenetic regulatory mechanisms in heart failure

M Sopic, EL Robinson, C Emanueli… - Basic Research in …, 2023 - Springer
The number of “omics” approaches is continuously growing. Among others, epigenetics has
appeared as an attractive area of investigation by the cardiovascular research community …

Microbiota implications in endocrine-related diseases: from development to novel therapeutic approaches

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2024 - mdpi.com
This comprehensive review article delves into the critical role of the human microbiota in the
development and management of endocrine-related diseases. We explore the complex …