Applications of machine learning to diagnosis and treatment of neurodegenerative diseases

MA Myszczynska, PN Ojamies, AMB Lacoste… - Nature reviews …, 2020 - nature.com
Globally, there is a huge unmet need for effective treatments for neurodegenerative
diseases. The complexity of the molecular mechanisms underlying neuronal degeneration …

[HTML][HTML] Individual differences in computational psychiatry: A review of current challenges

P Karvelis, MP Paulus, AO Diaconescu - Neuroscience & Biobehavioral …, 2023 - Elsevier
Bringing precision to the understanding and treatment of mental disorders requires
instruments for studying clinically relevant individual differences. One promising approach is …

[HTML][HTML] Revealing neurocomputational mechanisms of reinforcement learning and decision-making with the hBayesDM package

WY Ahn, N Haines, L Zhang - … Psychiatry (Cambridge, Mass.), 2017 - ncbi.nlm.nih.gov
Reinforcement learning and decision-making (RLDM) provide a quantitative framework and
computational theories with which we can disentangle psychiatric conditions into the basic …

[HTML][HTML] A tutorial on bridge sampling

QF Gronau, A Sarafoglou, D Matzke, A Ly… - Journal of mathematical …, 2017 - Elsevier
The marginal likelihood plays an important role in many areas of Bayesian statistics such as
parameter estimation, model comparison, and model averaging. In most applications …

The drift diffusion model as the choice rule in reinforcement learning

ML Pedersen, MJ Frank, G Biele - Psychonomic bulletin & review, 2017 - Springer
Current reinforcement-learning models often assume simplified decision processes that do
not fully reflect the dynamic complexities of choice processes. Conversely, sequential …

A causal account of the brain network computations underlying strategic social behavior

CA Hill, S Suzuki, R Polania, M Moisa… - Nature …, 2017 - nature.com
During competitive interactions, humans have to estimate the impact of their own actions on
their opponent's strategy. Here we provide evidence that neural computations in the right …

Altered learning under uncertainty in unmedicated mood and anxiety disorders

J Aylward, V Valton, WY Ahn, RL Bond… - Nature human …, 2019 - nature.com
Anxiety is characterized by altered responses under uncertain conditions, but the precise
mechanism by which uncertainty changes the behaviour of anxious individuals is unclear …

Theoretically informed generative models can advance the psychological and brain sciences: Lessons from the reliability paradox

Theories of individual differences are foundational to psychological and brain sciences, yet
they are traditionally developed and tested using superficial summaries of data (eg, mean …

A brain network supporting social influences in human decision-making

L Zhang, J Gläscher - Science advances, 2020 - science.org
Humans learn from their own trial-and-error experience and observing others. However, it
remains unknown how brain circuits compute expected values when direct learning and …

Hierarchical Bayesian parameter estimation for cumulative prospect theory

H Nilsson, J Rieskamp, EJ Wagenmakers - Journal of Mathematical …, 2011 - Elsevier
Cumulative prospect theory (CPT Tversky & Kahneman, 1992) has provided one of the most
influential accounts of how people make decisions under risk. CPT is a formal model with …