Machine learning for genetic prediction of psychiatric disorders: a systematic review
Abstract Machine learning methods have been employed to make predictions in psychiatry
from genotypes, with the potential to bring improved prediction of outcomes in psychiatric …
from genotypes, with the potential to bring improved prediction of outcomes in psychiatric …
Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD?
Background: Behavioral genetic studies provide strong evidence that attention‐
deficit/hyperactivity disorder (ADHD) has a substantial genetic component. Yet, due to the …
deficit/hyperactivity disorder (ADHD) has a substantial genetic component. Yet, due to the …
Germline genomic variants associated with childhood acute lymphoblastic leukemia
Abstract Using the Affymetrix 500K Mapping array and publicly available genotypes, we
identified 18 SNPs whose allele frequency differed significantly (P< 1× 10− 5) between …
identified 18 SNPs whose allele frequency differed significantly (P< 1× 10− 5) between …
The genetics of bipolar disorder: genome 'hot regions,'genes, new potential candidates and future directions
A Serretti, L Mandelli - Molecular psychiatry, 2008 - nature.com
Bipolar disorder (BP) is a complex disorder caused by a number of liability genes interacting
with the environment. In recent years, a large number of linkage and association studies …
with the environment. In recent years, a large number of linkage and association studies …
Statistical methods for genome-wide association studies
Genome-wide association studies (GWAS) detect common genetic variants associated with
complex disorders. With their comprehensive coverage of common single nucleotide …
complex disorders. With their comprehensive coverage of common single nucleotide …
G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis
SD Detera-Wadleigh, FJ McMahon - Biological psychiatry, 2006 - Elsevier
Association of the G72/G30 locus with schizophrenia and bipolar disorder has now been
reported in several studies. The G72/G30 locus may be one of several that account for the …
reported in several studies. The G72/G30 locus may be one of several that account for the …
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
Several independent studies and meta-analyses aimed at identifying genomic regions
linked to bipolar disorder (BP) have failed to find clear and consistent evidence of linkage …
linked to bipolar disorder (BP) have failed to find clear and consistent evidence of linkage …
Convergent functional genomics of genome‐wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms
H Le‐Niculescu, SD Patel, M Bhat… - American Journal of …, 2009 - Wiley Online Library
Given the mounting convergent evidence implicating many more genes in complex
disorders such as bipolar disorder than the small number identified unambiguously by the …
disorders such as bipolar disorder than the small number identified unambiguously by the …
Genome-wide association studies of schizophrenia and bipolar disorder in a diverse cohort of US veterans
Background Schizophrenia (SCZ) and bipolar disorder (BIP) are debilitating
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …
Reproductive cycle-associated mood symptoms in women with major depression and bipolar disorder
JL Payne, PS Roy, K Murphy-Eberenz… - Journal of affective …, 2007 - Elsevier
BACKGROUND: We sought to determine the prevalence of, and association between,
reproductive cycle-associated mood symptoms in women with affective disorders. We …
reproductive cycle-associated mood symptoms in women with affective disorders. We …