Latent tuberculosis: interaction of virulence factors in Mycobacterium tuberculosis

S Sundararajan, R Muniyan - Molecular Biology Reports, 2021 - Springer
Tuberculosis (TB) remains a prominent health concern worldwide. Besides extensive
research and vaccinations available, attempts to control the pandemic are cumbersome due …

Manipulation and Exploitation Of Host Immune System by Pathogenic Mycobacterium Tuberculosis for its Advantage

MA Mir, B Mir, M Kumawat, M Alkhanani… - Future Microbiology, 2022 - Taylor & Francis
Mycobacterium tuberculosis (Mtb) can become a long-term infection by evading the host
immune response. Coevolution of Mtb with humans has resulted in its ability to hijack the …

Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment

R Miggiano, M Rizzi, DM Ferraris - Pathogens, 2020 - mdpi.com
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis (MTB) and it represents a persistent public health threat for a number of …

Mycobacterium tuberculosis Uses Mce Proteins to Interfere With Host Cell Signaling

K Fenn, CT Wong, VC Darbari - Frontiers in molecular biosciences, 2020 - frontiersin.org
Tuberculosis continues to be the main cause for mortality by an infectious agent, making
Mycobacterium tuberculosis one of the most successful pathogens to survive for long …

Stealth strategies of Mycobacterium tuberculosis for immune evasion

MA Naeem, W Ahmad, R Tyagi, Q Akram… - Current Issues in …, 2021 - mdpi.com
Tuberculosis is a devastating disease causing high mortality all over the world, especially in
the developing countries. Mycobacterium tuberculosis (M. tb) is the causative agent of …

[HTML][HTML] Synthesis and structure–activity relationship of 1-(5-isoquinolinesulfonyl) piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH

V Singh, A Pacitto, S Donini, DM Ferraris… - European journal of …, 2019 - Elsevier
Tuberculosis (TB) is a major infectious disease associated increasingly with drug resistance.
Thus, new anti-tubercular agents with novel mechanisms of action are urgently required for …

Intelligent Mechanisms of Macrophage Apoptosis Subversion by Mycobacterium

AE Abdalla, H Ejaz, MO Mahjoob, AAM Alameen… - Pathogens, 2020 - mdpi.com
Macrophages are one of the first innate defense barriers and play an indispensable role in
communication between innate and adaptive immune responses, leading to restricted …

Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair

R Miggiano, C Morrone, F Rossi, M Rizzi - Molecules, 2020 - mdpi.com
Mycobacterium tuberculosis (MTB) is the causative agent of tuberculosis (TB), an ancient
disease which still today causes 1.4 million deaths worldwide per year. Long-term, multi …

Novel thiazolidinedione-hydroxamates as inhibitors of Mycobacterium tuberculosis virulence factor Zmp1

V Šlachtová, M Šebela, E Torfs, L Oorts… - European Journal of …, 2020 - Elsevier
Abstract Zinc metalloprotease 1 (Zmp1) is an extracellular enzyme, which has been found
essential for the intracellular survival and pathogenesis of Mycobacterium tuberculosis. In …

Natural epiestriol-16 act as potential lead molecule against prospective molecular targets of multidrug resistant Acinetobacter baumannii-Insight from in silico …

S Skariyachan, AG Muddebihalkar, V Badrinath… - Infection, Genetics and …, 2020 - Elsevier
The current study aimed to identify putative drug targets of multidrug resistant Acinetobacter
baumannii (MDRAb) and study the therapeutic potential of natural epiestriol-16 by computer …