Neurobiology of the incubation of drug craving: an update

JJ Chow, KM Pitts, K Negishi, R Madangopal… - Pharmacological …, 2024 - Elsevier
Relapse to drug use is often preceded by drug craving. Clinical observations in the 1980s
led clinical investigators to postulate that cue-induced cocaine craving may increase during …

Decreased incubation of fentanyl seeking in the absence of proximal drug-paired stimuli.

JR Yates, MR Broderick - Experimental and Clinical …, 2025 - psycnet.apa.org
Treating substance use disorders is difficult as individuals often resume substance use
during abstinence. One potential factor contributing to the recurrence of substance use is …

Fentanyl exposure alters rat CB1 receptor expression in the insula, nucleus accumbens and substantia nigra

Z Gacso, G Adamson, J Slama, C Xie, E Burdick… - Neuroscience …, 2025 - Elsevier
Prolonged periods of opioid use have been shown to cause neuroadaptations in the brain's
reward circuitry, contributing to addictive behaviors and drug dependence. Recently …

[HTML][HTML] PKCδ modulates SP1 mediated mitochondrial autophagy to exacerbate diacetylmorphine-induced ferroptosis in neurons

M Zhuang, S Zhu, L Su, L Liu, M Ji, C Dai, J Liu… - International …, 2024 - Elsevier
Diacetylmorphine (DA) is widely implicated in neuronal injury; however, the underlying
mechanisms remain unclear. We investigated the role of iron metamorphosis in DA-induced …

Opposite-sex pairing alters social interaction-induced GCaMP and dopamine activity in the insular cortex of male prairie voles

EM Vitale, AH Tbaba, K Tam, KR Gossman, AS Smith - bioRxiv, 2024 - biorxiv.org
The prairie vole (Microtus ochrogaster) is a monogamous rodent species which displays
selective social behaviors to conspecifics after establishing a pair bonded relationship …

From the body to the brain: Studying drug delivery and physiological interactions using MRI

M Dawson - 2024 - dspace.mit.edu
The brain is in continuous communication with the rest of the body. Nerves connect the
peripheral and central nervous system, and complex vasculature networks selectively permit …