African swine fever virus: a review

Z Li, W Chen, Z Qiu, Y Li, J Fan, K Wu, X Li, M Zhao… - Life, 2022 - mdpi.com
African swine fever (ASF) is a viral disease with a high fatality rate in both domestic pigs and
wild boars. ASF has greatly challenged pig-raising countries and also negatively impacted …

Current state of global African swine fever vaccine development under the prevalence and transmission of ASF in China

K Wu, J Liu, L Wang, S Fan, Z Li, Y Li, L Yi, H Ding… - Vaccines, 2020 - mdpi.com
African swine fever (ASF) is a highly lethal contagious disease of swine caused by African
swine fever virus (ASFV). At present, it is listed as a notifiable disease reported to the World …

pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production

J Li, J Song, L Kang, L Huang, S Zhou, L Hu… - PLoS …, 2021 - journals.plos.org
Inflammatory factors and type I interferons (IFNs) are key components of host antiviral innate
immune responses, which can be released from the pathogen-infected macrophages …

Deletion of the A137R gene from the pandemic strain of African swine fever virus attenuates the strain and offers protection against the virulent pandemic virus

DP Gladue, E Ramirez-Medina, E Vuono… - Journal of …, 2021 - Am Soc Microbiol
African swine fever virus (ASFV) is causing a devastating pandemic in domestic and wild
swine within an extended geographical area from Central Europe to East Asia, resulting in …

[HTML][HTML] African swine fever virus evasion of host defences

LK Dixon, M Islam, R Nash, AL Reis - Virus research, 2019 - Elsevier
African swine fever virus causes a haemorrhagic fever in domestic pigs and wild boar. The
continuing spread in Africa, Europe and Asia threatens the global pig industry. The lack of a …

Current status and evolving approaches to African swine fever vaccine development

T Teklue, Y Sun, M Abid, Y Luo… - … and emerging diseases, 2020 - Wiley Online Library
African swine fever (ASF) is a highly lethal haemorrhagic disease of swine caused by
African swine fever virus (ASFV), a unique and genetically complex virus. The disease …

Recombinant ASF live attenuated virus strains as experimental vaccine candidates

DP Gladue, MV Borca - Viruses, 2022 - mdpi.com
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical
area of the Eastern Hemisphere, from Central Europe to East and Southeast Asia, and …

African swine fever virus MGF360-12L inhibits type I interferon production by blocking the interaction of importin α and NF-κB signaling pathway

Y Zhuo, Z Guo, T Ba, C Zhang, L He, C Zeng, H Dai - Virologica Sinica, 2021 - Springer
African swine fever (ASF) is an infectious transboundary disease of domestic pigs and wild
boar and spreading throughout Eurasia. There is no vaccine and treatment available …

[HTML][HTML] Regulation of antiviral immune response by African swine fever virus (ASFV)

X Zheng, S Nie, WH Feng - Virologica Sinica, 2022 - Elsevier
African swine fever (ASF) is a highly contagious and acute hemorrhagic viral disease with a
high mortality approaching 100% in domestic pigs. ASF is an endemic in countries in sub …

African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D

G Zhao, T Li, X Liu, T Zhang, Z Zhang, L Kang… - Journal of Biological …, 2022 - ASBMB
African swine fever (ASF) is a viral hemorrhagic disease that affects domestic pigs and wild
boar and is caused by the African swine fever virus (ASFV). The ASFV virion contains a long …