Chemoenzymatic methods for the synthesis of glycoproteins

C Li, LX Wang - Chemical reviews, 2018 - ACS Publications
Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

Production of chitooligosaccharides and their potential applications in medicine

BB Aam, EB Heggset, AL Norberg, M Sørlie, KM Vårum… - Marine drugs, 2010 - mdpi.com
Chitooligosaccharides (CHOS) are homo-or heterooligomers of N-acetylglucosamine and D-
glucosamine. CHOS can be produced using chitin or chitosan as a starting material, using …

Toward automated enzymatic synthesis of oligosaccharides

L Wen, G Edmunds, C Gibbons, J Zhang… - Chemical …, 2018 - ACS Publications
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

TJ Boltje, T Buskas, GJ Boons - Nature chemistry, 2009 - nature.com
Synthetic oligosaccharides and glycoconjugates are increasingly used as probes for
biological research and as lead compounds for drug and vaccine discovery. These …

Enzymes in the synthesis of glycoconjugates

RM Schmaltz, SR Hanson, CH Wong - Chemical reviews, 2011 - ACS Publications
Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

Engineering of glycosidases and glycosyltransferases

SM Hancock, MD Vaughan, SG Withers - Current opinion in chemical …, 2006 - Elsevier
In recent years, substantial advances have been made in the engineering of glycosidases
and glycosyltransferases for the synthesis and degradation of glycan structures. Key …

Oligosaccharide synthesis by glycosynthases

G Perugino, A Trincone, M Rossi, M Moracci - TRENDS in Biotechnology, 2004 - cell.com
Oligosaccharide synthesis is becoming increasingly important to the pharmaceutical
industry because these biomolecules have potential application as therapeutics. Enzymatic …

Synthesis of glycosides by glycosynthases

MR Hayes, J Pietruszka - Molecules, 2017 - mdpi.com
The many advances in glycoscience have more and more brought to light the crucial role of
glycosides and glycoconjugates in biological processes. Their major influence on the …

Biotechnological approaches for field applications of chitooligosaccharides (COS) to induce innate immunity in plants

SN Das, J Madhuprakash, P Sarma… - Critical Reviews in …, 2015 - Taylor & Francis
Plants have evolved mechanisms to recognize a wide range of pathogen-derived molecules
and to express induced resistance against pathogen attack. Exploitation of induced …

Enzymatic synthesis of artificial polysaccharides

PJ Smith, ME Ortiz-Soto, C Roth… - ACS Sustainable …, 2020 - ACS Publications
Polysaccharides are the most important renewable polymers on Earth and hold an
enormous potential for the production of ecofriendly functional materials. In addition to being …