The use of privileged structures in drug discovery has proven to be an effective strategy,
allowing the generation of innovative hits/leads and successful optimization processes …

Secondary metabolites of higher fungi (mushrooms) are an underexplored resource
compared to plant-derived secondary metabolites. An increasing interest in mushroom …

Cyclodipeptides, called 2, 5-diketopiperazines (2, 5-DKPs), are obtained by the
condensation of two amino acids. Fungi have been considered to be a rich source of novel …

Covering: 2012 to 2022 Ten-membered lactones (TMLs) are an interesting and diverse
group of natural polyketides that are abundant in fungi and, to a lesser extent, in bacteria …

Chromone glycosides comprise an important group of secondary metabolites. They are
widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant …

Armillaria mellea is a major plant pathogen. Yet, no large-scale “-omics” data are available
to enable new studies, and limited experimental models are available to investigate …

Two previous unreported epipolythiodioxopiperazines of the emestrin family, namely,
noremestrin A (1) and secoemestrin E (2), were successfully isolated from the fungal source …

Prenylemestrins A and B (1 and 2, respectively), two unusual epipolythiodioxopiperazines
featuring a thioethanothio bridge instead of a polysulfide bridge, were isolated from the …

Armillaria is one of the most common diseases underlying chronic root rot in woody plants.
Although there is no particularly effective way to prevent it, soil disinfection is a common …

Ascomycetes belonging to the order Sordariales are a well-known reservoir of secondary
metabolites with potential beneficial applications. Species of the Sordariales are ubiquitous …