[HTML][HTML] Calcium phosphates in biomedical applications: materials for the future?

W Habraken, P Habibovic, M Epple, M Bohner - Materials today, 2016 - Elsevier
Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Calcium phosphate cements for bone engineering and their biological properties

HHK Xu, P Wang, L Wang, C Bao, Q Chen, MD Weir… - Bone research, 2017 - nature.com
Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their
discovery in the 1980s, extensive research has been conducted to improve their properties …

Biomimetic porous scaffolds for bone tissue engineering

S Wu, X Liu, KWK Yeung, C Liu, X Yang - Materials Science and …, 2014 - Elsevier
Increased use of reconstruction procedures in orthopedics, due to trauma, tumor, deformity,
degeneration and an aging population, has caused a blossom, not only in surgical …

How smart do biomaterials need to be? A translational science and clinical point of view

BM Holzapfel, JC Reichert, JT Schantz… - Advanced drug delivery …, 2013 - Elsevier
Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and …

[HTML][HTML] Biomaterial-induced pathway modulation for bone regeneration

S Vermeulen, ZT Birgani, P Habibovic - Biomaterials, 2022 - Elsevier
Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …

Bioceramics to regulate stem cells and their microenvironment for tissue regeneration

Y Zhou, C Wu, J Chang - Materials Today, 2019 - Elsevier
Bioceramics have been used for the replacement and repair of damaged hard tissues for
about 50 years, in which the mechanical properties and biocompatibility of the materials are …

Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells

P Wang, L Zhao, J Liu, MD Weir, X Zhou, HHK Xu - Bone research, 2014 - nature.com
Tissue engineering is promising to meet the increasing need for bone regeneration.
Nanostructured calcium phosphate (CaP) biomaterials/scaffolds are of special interest as …

[HTML][HTML] Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis

SR Khan - Translational andrology and urology, 2014 - ncbi.nlm.nih.gov
Calcium oxalate (CaOx) kidney stones are formed attached to Randall's plaques (RPs) or
Randall's plugs. Mechanisms involved in the formation and growth are poorly understood. It …

Bioinorganics and biomaterials: bone repair

P Habibovic, JE Barralet - Acta biomaterialia, 2011 - Elsevier
The field of bioinorganics is well established in the development of a variety of therapies.
However, their application to bone regeneration, specifically by way of localized delivery …

Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies

YC Chai, A Carlier, J Bolander, SJ Roberts, L Geris… - Acta biomaterialia, 2012 - Elsevier
Calcium phosphate (CaP) has traditionally been used for the repair of bone defects because
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …