Isolevuglandins as mediators of disease and the development of dicarbonyl scavengers as pharmaceutical interventions

SS Davies, LS May-Zhang, O Boutaud… - Pharmacology & …, 2020 - Elsevier
Products of lipid peroxidation include a number of reactive lipid aldehydes such as
malondialdehyde, 4-hydroxy-nonenal, 4-oxo-nonenal, and isolevuglandins (IsoLGs) …

Paal–Knorr synthesis of pyrroles: from conventional to green synthesis

A Balakrishna, A Aguiar, PJM Sobral, MY Wani… - Catalysis …, 2019 - Taylor & Francis
The pyrrole molecular framework is found in a large number of natural and synthetic
compounds of great importance. Since functionalized pyrroles are essential for the progress …

Metal-free synthesis of imidazoles and 2-aminoimidazoles

N Saha, PJ Wanjari, G Dubey, N Mahawar… - Journal of Molecular …, 2023 - Elsevier
Imidazole ring is an important scaffold in many biologically important molecules. Many
methods have been reported for the synthesis of imidazoles. Several methods of generating …

Elucidation of reaction pathways of nitrogenous species by hydrothermal liquefaction process of model compounds

A Matayeva, D Bianchi, S Chiaberge, F Cavani… - Fuel, 2019 - Elsevier
The reaction pathway of nitrogen containing compounds under hydrothermal liquefaction
(HTL) conditions was investigated by using amino acids as protein model compounds. The …

Ascorbic acid as a multifunctional hydrogen bonding catalyst for Paal–Knorr synthesis of N-substituted mono- and bis-pyrroles: experimental and theoretical aspects

A Ghaemi, HR Darabi, K Aghapoor… - Research on Chemical …, 2023 - Springer
Ascorbic acid could be applied as a recyclable organocatalyst for the preparation of pyrroles
via Paal–Knorr condensation of hexane-2, 5-dione with various mono-and diamines. The …

A green and efficient method for the synthesis of pyrroles using a deep eutectic solvent ([CholineCl][ZnCl 2] 3) under solvent-free sonication

HT Nguyen, DKN Chau, PH Tran - New Journal of Chemistry, 2017 - pubs.rsc.org
An efficient deep eutectic solvent-based synthesis of pyrroles under ultrasound irradiation
has been developed to provide a significant improvement of the yield up to 99% in a short …

Recent Advances in Synthetic Methods for 2H‐Pyrroles

SM Choi, JH Kim - Advanced Synthesis & Catalysis, 2024 - Wiley Online Library
Abstract The compound, 2H‐pyrrole, is a key scaffold contained in natural products,
bioactive compounds, pharmaceuticals, and organic functional materials. However, the …

Efficient Synthesis of Biomass‐Derived N‐Substituted 2‐Hydroxymethyl‐5‐Methyl‐Pyrroles in Two Steps from 5‐Hydroxymethylfurfural

B Wozniak, Y Li, S Hinze, S Tin… - European Journal of …, 2018 - Wiley Online Library
An efficient two‐step synthesis for the conversion of biomass‐derived 5‐hydroxymethyl‐
furfural (HMF) to a variety of N‐substituted 2‐hydroxymethyl‐5‐methylpyrroles was …

Modular microreactor with integrated reflection element for online reaction monitoring using infrared spectroscopy

JJA Lozeman, T Elsbecker, S Bohnenn, HL de Boer… - Lab on a Chip, 2020 - pubs.rsc.org
We report on the fabrication of an internal reflection element (IRE) combined with a modular
polymer microfluidic chip that can be used for attenuated total reflection (ATR) infrared …

A convenient approach for the synthesis of substituted pyrroles by using phosphoric acid as a catalyst and their photophysical properties

YA Ibrahim, J Li, L Ai, B Li - Journal of Molecular Structure, 2022 - Elsevier
Twenty-three new pyrrole compounds aside from six knowns, including the synthetically
challenging tetra-and penta-substituted pyrroles from the corresponding 1, 4-dicarbonyl …