[HTML][HTML] Multi-omics in Crohn's disease: New insights from inside

C Mu, Q Zhao, Q Zhao, L Yang, X Pang, T Liu… - Computational and …, 2023 - Elsevier
Crohn's disease (CD) is an inflammatory bowel disease (IBD) with complex clinical
manifestations such as chronic diarrhea, weight loss and hematochezia. Despite the …

New approaches to secondary metabolite discovery from anaerobic gut microbes

LV Butkovich, OB Vining, MA O'Malley - Applied Microbiology and …, 2025 - Springer
The animal gut microbiome is a complex system of diverse, predominantly anaerobic
microbiota with secondary metabolite potential. These metabolites likely play roles in …

Evaluating the prebiotic effect of oligosaccharides on gut microbiome wellness using in vitro fecal fermentation

DH Lee, H Seong, D Chang, VK Gupta, J Kim… - npj Science of …, 2023 - nature.com
We previously proposed the Gut Microbiome Wellness Index (GMWI), a predictor of disease
presence based on a gut microbiome taxonomic profile. As an application of this index for …

Mining metagenomic data to gain a new insight into the gut microbial biosynthetic potential in placental mammals

D Hu, T Zhang, S He, T Pu, Y Yin, Y Hu - Microbiology Spectrum, 2024 - journals.asm.org
Mammals host a remarkable diversity and abundance of gut microbes. Biosynthetic gene
clusters (BGCs) in microbial genomes encode biologically active chemical products and …

GMWI-webtool: a user-friendly browser application for assessing health through metagenomic gut microbiome profiling

D Chang, VK Gupta, B Hur, KY Cunningham… - …, 2023 - academic.oup.com
We recently introduced the Gut Microbiome Wellness Index (GMWI), a stool metagenome-
based indicator for assessing health by determining the likelihood of disease given the state …

Bacteriocin Classification, Prediction and Applications

G Wang - Antimicrobial Peptides from Lactic Acid Bacteria …, 2024 - Springer
Bacteriocins from lactic acid bacteria are gene-coded small bacterial proteins that offer
advantages to the producer strains. Initially discovered almost 100 years ago, bacteriocins …

FunBGC: An Intelligent Framework for Fungal Biosynthetic Gene Cluster Identification

Y Wang, Y Wang - International Symposium on Bioinformatics Research …, 2024 - Springer
Biosynthetic gene clusters (BGCs) in bacterial and fungal genomes encode bioactive
secondary metabolites, which play a crucial role in many therapeutic applications in the …