[HTML][HTML] The pharmacology of resveratrol in animals and humans

EJ Park, JM Pezzuto - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2015 - Elsevier
In addition to thousands of research papers related to resveratrol (RSV), approximately 300
review articles have been published. Earlier research tended to focus on pharmacological …

Current progress and outlook of nano-based hydrogel dressings for wound healing

X Zhang, P Wei, Z Yang, Y Liu, K Yang, Y Cheng… - Pharmaceutics, 2022 - mdpi.com
Wound dressing is an important tool for wound management. Designing wound dressings
by combining various novel materials and drugs to optimize the peri-wound environment …

In situ formed anti-inflammatory hydrogel loading plasmid DNA encoding VEGF for burn wound healing

P Wang, S Huang, Z Hu, W Yang, Y Lan, J Zhu… - Acta biomaterialia, 2019 - Elsevier
Excessive inflammation and reduced angiogenesis are two major obstacles in burn wound
healing and skin regeneration. Here we report the fabrication and application of a …

Metformin limits osteoarthritis development and progression through activation of AMPK signalling

J Li, B Zhang, WX Liu, K Lu, H Pan, T Wang… - Annals of the …, 2020 - ard.bmj.com
Objectives In this study, we aim to determine the effect of metformin on osteoarthritis (OA)
development and progression. Methods Destabilisation of the medial meniscus (DMM) …

A female-specific role for calcitonin gene-related peptide (CGRP) in rodent pain models

C Paige, I Plasencia-Fernandez, M Kume… - Journal of …, 2022 - Soc Neuroscience
We aimed to investigate a sexually dimorphic role of calcitonin gene-related peptide (CGRP)
in rodent models of pain. Based on findings in migraine where CGRP has a preferential pain …

Molecular properties of red wine compounds and cardiometabolic benefits

MM Markoski, J Garavaglia, A Oliveira… - Nutrition and …, 2016 - journals.sagepub.com
Wine has been used since the dawn of human civilization. Despite many health benefits,
there is still a lot of discussion about the real properties of its components and its actions on …

Epigenetic modifications associated to neuroinflammation and neuropathic pain after neural trauma

C Penas, X Navarro - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Accumulating evidence suggests that epigenetic alterations lie behind the induction and
maintenance of neuropathic pain. Neuropathic pain is usually a chronic condition caused by …

Commonalities between pain and memory mechanisms and their meaning for understanding chronic pain

TJ Price, KE Inyang - Progress in molecular biology and translational …, 2015 - Elsevier
Pain sensing neurons in the periphery (called nociceptors) and the central neurons that
receive their projections show remarkable plasticity following injury. This plasticity results in …

Translational control mechanisms in persistent pain

A Khoutorsky, TJ Price - Trends in neurosciences, 2018 - cell.com
Persistent pain, which is poorly treated and estimated to afflict one third of the world's
population, is largely mediated by the sensitization of nociceptive neurons. This sensitization …

Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy

A Yadav, SS Yadav, S Singh, R Dabur - European Journal of …, 2022 - Elsevier
The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …