The universal increase in the number of patients with nonhealing skin wounds imposes a
huge social and economic burden on the patients and healthcare systems. Although, the …

Macrophages play a prominent role in wound healing. In the early stages, they promote
inflammation and remove pathogens, wound debris, and cells that have apoptosed. Later in …

It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …

Regeneration and tissue repair processes consist of a sequence of molecular and cellular
events which occur after the onset of a tissue lesion in order to restore the damaged tissue …

Wound healing studies are intricate, mainly because of the multifaceted nature of the wound
environment and the complexity of the healing process, which integrates a variety of cells …

The clinical treatment of chronic wounds caused by different pathophysiological ulcers like
diabetic ulcers still remains a bottleneck. Although numerous approaches have been …

Macrophages and inflammation play a beneficial role during wound repair with
macrophages regulating a wide range of processes, such as removal of dead cells, debris …

Significance: The immune system plays a central role in orchestrating the tissue healing
process. Hence, controlling the immune system to promote tissue repair and regeneration is …

Background Indications for the use of negative pressure wound therapy (NPWT) are broad
and include prophylaxis for surgical site infections (SSIs). Existing evidence for the …

A wound is the loss of the normal integrity, structure, and functions of the skin due to a
physical, chemical, or mechanical agent. Wound repair consists of an orderly and complex …