Neutrophils are the first line of defense against bacteria and fungi and help combat parasites
and viruses. They are necessary for mammalian life, and their failure to recover after …

Neutrophils are part of a family of granulocytes that, together with eosinophils and basophils,
play an essential role in innate immunity. Neutrophils are the most abundant circulating …

Tumor-associated macrophages (TAMs) can influence ovarian cancer growth, migration,
and metastasis, but the detailed mechanisms underlying ovarian cancer metastasis remain …

Neutrophils respond nearly instantly to infection, rapidly deploying a potent enzymatic and
chemical arsenal immediately upon entering an infected site. This capacity for rapid and …

Purpose: The phenotypic manifestations of cerebral cavernous malformation disease
caused by rare PDCD10 mutations have not been systematically examined, and a …

Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

Abstract Cerebral Cavernous Malformation (CCM) is a vascular disease of proven genetic
origin, which may arise sporadically or is inherited as an autosomal dominant condition with …

Loss-of-function mutations in genes encoding KRIT1 (also known as CCM1), CCM2 (also
known as OSM and malcavernin) or PDCD10 (also known as CCM3) cause cerebral …

Cerebral cavernous malformations (CCMs) are vascular abnormalities that primarily occur in
adulthood and cause cerebral hemorrhage, stroke, and seizures. CCMs are thought to be …

Cerebral cavernous malformations (CCMs) are vascular malformations that affect the central
nervous system and result in cerebral hemorrhage, seizure and stroke. CCMs arise from …