Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

Inhalable GSH-Triggered Nanoparticles to Treat Commensal Bacterial Infection in In Situ Lung Tumors

Z Ma, H Wang, Z Shi, F Yan, Q Li, J Chen, ZK Cui… - ACS …, 2023 - ACS Publications
Bacterial infection has been considered one of the primary reasons for low survival rate of
lung cancer patients. Herein, we demonstrated that a kind of mesoporous silica …

[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

[HTML][HTML] Nonordered dendritic mesoporous silica nanoparticles as promising platforms for advanced methods of diagnosis and therapies

S Malekmohammadi, RUR Mohammed… - Materials Today …, 2022 - Elsevier
Dendritic mesoporous silica nanoparticles (DMSNs) are a new generation of porous
materials that have gained great attention compared to other mesoporous silicas due to …

Mesoporous silica nanoparticles as carrier to overcome bacterial drug resistant barriers

J Zhuang, Y Yu, R Lu - International Journal of Pharmaceutics, 2023 - Elsevier
Antibiotic resistance has become a global threat to health due to abuse of antibiotics. Lots of
existing antibiotics have lost their effect on drug resistant bacteria. Moreover, the discovery …

[HTML][HTML] Straightforward adsorption-based formulation of mesoporous silica nanoparticles for drug delivery applications

R Schmid, N Neffgen, M Lindén - Journal of Colloid and Interface Science, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have emerged as a very promising drug delivery
platform. However, multi-step synthesis and surface functionalization protocols rise the …

Conjugation of antimicrobial peptides to enhance therapeutic efficacy

SP Selvaraj, JY Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Pulmonary delivery systems for antimicrobial peptides

L Caselli, GR Rodrigues, OL Franco… - Critical Reviews in …, 2023 - Taylor & Francis
Bacterial infections of the respiratory tract cause millions of deaths annually. Several
diseases exist wherein (1) bacterial infection is the main cause of disease (eg, tuberculosis …

[HTML][HTML] Antimicrobial peptides against bacterial pathogens: Innovative delivery nanosystems for pharmaceutical applications

E Imperlini, F Massaro, F Buonocore - Antibiotics, 2023 - mdpi.com
The introduction of antibiotics has revolutionized the treatment and prevention of microbial
infections. However, the global spread of pathogens resistant to available antibiotics is a …