Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

CADASIL is a complex, devastating disease with unknown mechanism and no treatment
options. As we increase our understanding of CADASIL, translational research bridging …

Background Assessing the glymphatic function using diffusion tensor image analysis along
the perivascular space (DTI‐ALPS) may be helpful for mild traumatic brain injury (mTBI) …

It is suggested that the brain's peak width of skeletonized water mean diffusivity (PSMD) is a
neuro-biomarker of processing speed, an important aspect of cognitive aging. We tested …

Background The peak width of skeletonized mean diffusivity (PSMD) has been proposed as
a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We …

Objectives To test the hypotheses that peak skeletonized mean diffusivity (PSMD), a
measure of cerebral white matter microstructural disruption, is 1) increased in patients with …

Birth weight, an indicator of fetal growth, is associated with cognitive outcomes in early life
(which are predictive of cognitive ability in later life) and risk of metabolic and cardiovascular …

Background Peak width of skeletonized mean diffusivity (PSMD) is a promising diffusion
tensor imaging (DTI) marker that shows consistent and strong cognitive associations in the …

Diffusion tensor imaging (DTI) is a noninvasive, quantitative MRI technique that measures
white matter (WM) integrity. Many brain dimensions are heritable, including white matter …

Preterm birth is closely associated with cognitive impairment and generalized
dysconnectivity of neural networks inferred from water diffusion MRI (dMRI) metrics. Peak …