The nuclear receptor PPARγ is a master regulator of adipogenesis. PPARγ is highly
expressed in adipose tissues and its expression is markedly induced during adipogenesis …

Adipocyte differentiation is tightly controlled by a transcriptional cascade, which directs the
extensive reprogramming of gene expression required to convert fibroblast-like precursor …

Adipogenesis is tightly controlled by a complex network of transcription factors acting at
different stages of differentiation. Peroxisome proliferator‐activated receptor γ (PPARγ) and …

Objective: The development of obesity is inseparable from genetic and epigenetic factors,
and transcription factors (TFs) play an essential role in these two mechanisms. This review …

Mutations in SOX10 cause neurocristopathies which display varying degrees of
hypopigmentation. Using a sensitized mutagenesis screen, we identified Smarca4 as a …

Glucocorticoids play an important role in adipogenesis through the glucocorticoid receptor
(GR) that forms a heterocomplex with Hsp90• Hsp70 and one high molecular weight …

Regulation of adipose tissue formation by adipogenic-regulatory proteins has long been a
topic of interest given the ever-increasing health concerns of obesity and type 2 diabetes in …

The most common complications in patients with type-2 diabetes are hyperglycemia and
hyperlipidemia that can lead to cardiovascular disease. Alleviation of these complications …

Understanding the molecular pathways that enhance β‐cell proliferation, survival, and
insulin secretion may be useful to improve treatments for diabetes. Nkx6. 1 induces …

Background Excessive accumulation of adipose tissue in cultured fish is an outstanding
problem in aquaculture. To understand the development of adiposity, it is crucial to identify …