Oxidative stress in age-related macular degeneration: Nrf2 as therapeutic target

I Bellezza - Frontiers in pharmacology, 2018 - frontiersin.org
Age-related macular degeneration is one of the leading causes of vision loss in the elderly.
Genetics, environmental insults, and age-related issues are risk factors for the development …

[HTML][HTML] Glyoxalase system: A systematic review of its biological activity, related-diseases, screening methods and small molecule regulators

Y He, C Zhou, M Huang, C Tang, X Liu, Y Yue… - Biomedicine & …, 2020 - Elsevier
The glyoxalase system is a ubiquitous enzymatic network which plays important roles in
biological life. It consists of glyoxalase 1 (GLO1), glyoxalase 2 (GLO2), and reduced …

Osteoporosis in COPD patients: Risk factors and pulmonary rehabilitation

Y Li, H Gao, L Zhao, J Wang - The Clinical Respiratory Journal, 2022 - Wiley Online Library
Objectives To present a review on the pathogenesis, risk factor and treatment of chronic
obstructive pulmonary disease complicated with osteoporosis and provide new ideas for the …

[HTML][HTML] The role of RAGE in host pathology and crosstalk between RAGE and TLR4 in innate immune signal transduction pathways

D Prantner, S Nallar, SN Vogel - FASEB journal: official publication …, 2020 - ncbi.nlm.nih.gov
Although the innate immune receptor protein, Receptor for Advanced Glycation End
products (RAGE), has been extensively studied, there has been renewed interest in RAGE …

Diabetes mellitus promotes susceptibility to periodontitis—novel insight into the molecular mechanisms

M Zhao, Y Xie, W Gao, C Li, Q Ye, Y Li - Frontiers in endocrinology, 2023 - frontiersin.org
Diabetes mellitus is a main risk factor for periodontitis, but until now, the underlying
molecular mechanisms remain unclear. Diabetes can increase the pathogenicity of the …

[HTML][HTML] Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity

J Ebersole, V Samburova, Y Son… - Tobacco induced …, 2020 - ncbi.nlm.nih.gov
Use of electronic nicotine delivery systems (ENDS), such as electronic cigarettes (e-cigs), is
increasing across the US population and is particularly troubling due to their adoption by …

An overlooked bone metabolic disorder: cigarette smoking-induced osteoporosis

W Weng, H Li, S Zhu - Genes, 2022 - mdpi.com
Cigarette smoking (CS) leads to significant bone loss, which is recognized as an
independent risk factor for osteoporosis. The number of smokers is continuously increasing …

Associations between smoke exposure and osteoporosis or osteopenia in a US NHANES population of elderly individuals

W Hou, S Chen, C Zhu, Y Gu, L Zhu… - Frontiers in …, 2023 - frontiersin.org
Background Tobacco exposure is considered to be a risk factor for reduced bone mineral
density (BMD), which may result in osteopenia. Cotinine, a metabolite of nicotine, is …

Curcumin Prevents Diabetic Osteoporosis through Promoting Osteogenesis and Angiogenesis Coupling via NF‐κB Signaling

D Fan, J Lu, N Yu, Y Xie, L Zhen - … ‐Based Complementary and …, 2022 - Wiley Online Library
Diabetic osteoporosis (DOP) is a metabolic disease which is characterized by impaired
bone microarchitecture and reduced bone mineral density resulting from hyperglycemia …

Nicotine and cotinine inhibit catalase and glutathione reductase activity contributing to the impaired osteogenesis of SCP‐1 cells exposed to cigarette smoke

RH Aspera-Werz, S Ehnert, D Heid… - Oxidative Medicine …, 2018 - Wiley Online Library
Cigarette smoking has been identified as a major risk factor for osteoporosis decades ago.
Several studies have shown a direct relationship between cigarette smoking, decreased …