Myelodysplastic syndromes: 2023 update on diagnosis, risk‐stratification, and management

G Garcia‐Manero - American journal of hematology, 2023 - Wiley Online Library
Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

T De Witte, D Bowen, M Robin… - Blood, The Journal …, 2017 - ashpublications.org
An international expert panel, active within the European Society for Blood and Marrow
Transplantation, European LeukemiaNet, Blood and Marrow Transplant Clinical Trial Group …

Real-world validation of molecular international prognostic scoring system for myelodysplastic syndromes

E Sauta, M Robin, M Bersanelli, E Travaglino… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Myelodysplastic syndromes (MDS) are heterogeneous myeloid neoplasms in
which a risk-adapted treatment strategy is needed. Recently, a new clinical-molecular …

Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation

RC Lindsley, W Saber, BG Mar, R Redd… - … England Journal of …, 2017 - Mass Medical Soc
Background Genetic mutations drive the pathogenesis of the myelodysplastic syndrome
(MDS) and are closely associated with clinical phenotype. Therefore, genetic mutations may …

Biologic assignment trial of reduced-intensity hematopoietic cell transplantation based on donor availability in patients 50-75 years of age with advanced …

R Nakamura, W Saber, MJ Martens… - Journal of clinical …, 2021 - ascopubs.org
PURPOSE Allogeneic hematopoietic cell transplantation (HCT) is the only potentially
curative therapy for myelodysplastic syndromes (MDS), although it is infrequently offered to …

Treatment of MDS

U Platzbecker - Blood, The Journal of the American Society of …, 2019 - ashpublications.org
The heterogeneous nature of myelodysplastic syndromes (MDS) demands a complex and
personalized variety of therapeutic approaches. Among them, allogeneic hematopoietic …

Diagnosis and treatment of myelodysplastic syndromes: a review

MA Sekeres, J Taylor - Jama, 2022 - jamanetwork.com
Importance Myelodysplastic neoplasms (MDS), formerly known as myelodysplastic
syndromes, are clonal hematopoietic malignancies that cause morphologic bone marrow …

Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet

L Malcovati, E Hellström-Lindberg… - Blood, The Journal …, 2013 - ashpublications.org
Within the myelodysplastic syndrome (MDS) work package of the European LeukemiaNet,
an Expert Panel was selected according to the framework elements of the National Institutes …

Myelodysplastic syndromes, version 2.2017, NCCN clinical practice guidelines in oncology

PL Greenberg, RM Stone, A Al-Kali, SK Barta… - Journal of the National …, 2017 - jnccn.org
The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid
disorders with a highly variable disease course. Diagnostic criteria to better stratify patients …

Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation

T Yoshizato, Y Nannya, Y Atsuta… - Blood, The Journal …, 2017 - ashpublications.org
Genetic alterations, including mutations and copy-number alterations, are central to the
pathogenesis of myelodysplastic syndromes and related diseases (myelodysplasia), but …