[HTML][HTML] Molecular basis of bacterial disinfectant resistance

S Mc Carlie, CE Boucher, RR Bragg - Drug Resistance Updates, 2020 - Elsevier
Antibiotic resistance could accelerate humanity towards an already fast-approaching post-
antibiotic era, where disinfectants and effective biosecurity measures will be critically …

One system for all: is mass spectrometry a future alternative for conventional antibiotic susceptibility testing?

M Welker, A Van Belkum - Frontiers in microbiology, 2019 - frontiersin.org
The two main pillars of clinical microbiological diagnostics are the identification of potentially
pathogenic microorganisms from patient samples and the testing for antibiotic susceptibility …

Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin

R Roemhild, M Linkevicius, DI Andersson - PLoS biology, 2020 - journals.plos.org
Antibiotic resistance increasingly limits the success of antibiotic treatments, and physicians
require new ways to achieve efficient treatment despite resistance. Resistance mechanisms …

[HTML][HTML] Integrated metagenomic and metatranscriptomic profiling reveals differentially expressed resistomes in human, chicken, and pig gut microbiomes

Y Wang, Y Hu, F Liu, J Cao, N Lv, B Zhu, G Zhang… - Environment …, 2020 - Elsevier
Gut microbiota is a reservoir of antibiotic resistance genes (ARGs). Yet, limited information is
available regarding the presence (metagenomic DNA level) and expression profiles …

Enhance antibiotic resistance and human health risks in aerosols during the COVID-19 pandemic

Q Wang, C Liu, S Sun, G Yang, J Luo, N Wang… - Science of The Total …, 2023 - Elsevier
Aerosols are an important route for the transmission of antibiotic resistance genes (ARGs).
Since the 2019 (COVID-19) pandemic, the large-scale use of disinfectants has effectively …

Metabolomics-driven exploration of the chemical drug space to predict combination antimicrobial therapies

AI Campos, M Zampieri - Molecular cell, 2019 - cell.com
Alternative to the conventional search for single-target, single-compound treatments,
combination therapies can open entirely new opportunities to fight antibiotic resistance …

Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection

KJ Card, T LaBar, JB Gomez, RE Lenski - PLoS biology, 2019 - journals.plos.org
Populations often encounter changed environments that remove selection for the
maintenance of particular phenotypic traits. The resulting genetic decay of those traits under …

Meta-analysis of microbiomes reveals metagenomic features of fermented vegetables

Y Liu, L Yu, F Tian, W Chen, Q Zhai - Food Research International, 2023 - Elsevier
An insightful exploration of the fermented vegetable microbiome is the key to improving food
quality and sustainability. Based on 57 fermented vegetable samples from China, Ireland …

Targeted Transcriptional Activation Using a CRISPR-Associated Transposon System

AM Garza Elizondo, J Chappell - ACS Synthetic Biology, 2023 - ACS Publications
Synthetic perturbation of gene expression is central to our ability to reliably uncover
genotype–phenotype relationships in microbes. Here, we present a novel transcription …

Ecology, more than antibiotics consumption, is the major predictor for the global distribution of aminoglycoside-modifying enzymes

L Pradier, S Bedhomme - Elife, 2023 - elifesciences.org
Antibiotic consumption and its abuses have been historically and repeatedly pointed out as
the major driver of antibiotic resistance emergence and propagation. However, several …