Simple Summary The tumor immune escape mechanisms are key factors in cancer
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …

Natural killer (NK) cells contribute to the first line of defense against viruses and to the
control of tumor growth and metastasis spread. The discovery of HLA class I specific …

Typical genotyping workflows map reads to a reference genome before identifying genetic
variants. Generating such alignments introduces reference biases and comes with …

Abstract The Allele Frequency Net Database (AFND, www. allelefrequencies. net) provides
the scientific community with a freely available repository for the storage of frequency data …

During early human pregnancy the uterine mucosa transforms into the decidua, into which
the fetal placenta implants and where placental trophoblast cells intermingle and …

Induced pluripotent stem cells (iPSCs) constitute a potential source of autologous patient-
specific cardiomyocytes for cardiac repair, providing a major benefit over other sources of …

Twenty‐five years ago, in 1998, the HLA Informatics Group of the Anthony Nolan Research
Institute released the IMGT/HLA Database. Since this time, this online resource has acted as …

Stimulation or tolerance of natural killer (NK) cells is achieved through a cross‐talk of signals
derived from cell surface activating and inhibitory receptors. Killer cell immunoglobulin‐like …

Cancer immunotherapy targeting the TIGIT/PVR pathway is currently facing challenges.
KIR2DL5, a member of the human killer cell, immunoglobulin-like receptor (KIR) family, has …

Abstract The IPD-MHC Database project (http://www. ebi. ac. uk/ipd/mhc/) collects and
expertly curates sequences of the major histocompatibility complex from non-human species …