Applications of proteomics in ovarian cancer: dawn of a new era

A Ghose, SVN Gullapalli, N Chohan, A Bolina… - Proteomes, 2022 - mdpi.com
The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The
patients present an advanced stage at diagnosis. This heterogeneous disease has …

BRCA mutations in ovarian and prostate cancer: bench to bedside

S Boussios, E Rassy, M Moschetta, A Ghose… - Cancers, 2022 - mdpi.com
Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …

Recent insights into PARP and immuno-checkpoint inhibitors in epithelial ovarian cancer

A Revythis, A Limbu, C Mikropoulos, A Ghose… - International journal of …, 2022 - mdpi.com
Ovarian cancer is one of the most common gynecologic cancers and has the highest
mortality rate of any other cancer of the female reproductive system. Epithelial ovarian …

Epithelial ovarian cancer: providing evidence of predisposition genes

S Shah, A Cheung, M Kutka, M Sheriff… - International Journal of …, 2022 - mdpi.com
Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors.
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …

Non-epithelial ovarian cancers: how much do we really know?

A Cheung, S Shah, J Parker, P Soor, A Limbu… - International journal of …, 2022 - mdpi.com
Non-epithelial ovarian cancers (NEOC) are a group of uncommon malignancies that mainly
includes germ cell tumours (GCT), sex cord-stromal tumours (SCST), and some extremely …

BRCA mutations in prostate cancer: assessment, implications and treatment considerations

S Shah, R Rachmat, S Enyioma, A Ghose… - International Journal of …, 2021 - mdpi.com
Prostate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is
implicated in cancer and DNA damage response (DDR) pathways are in place against this …

Angiogenesis and anti-angiogenic treatment in prostate cancer: mechanisms of action and molecular targets

E Ioannidou, M Moschetta, S Shah, JS Parker… - International journal of …, 2021 - mdpi.com
Prostate cancer (PC) is the most common cancer in men and the second leading cause of
cancer-related death worldwide. Many therapeutic advances over the last two decades have …

Advances in ovarian cancer treatment beyond PARP inhibitors

F Aliyuda, M Moschetta, A Ghose… - Current Cancer Drug …, 2023 - ingentaconnect.com
Ovarian cancer has become the largest cause of gynaecological cancer-related mortality. It
is typically diagnosed at a late stage and has no effective screening strategy. Ovarian cancer …

Clinical challenges in the management of malignant ovarian germ cell tumours

I Saani, N Raj, R Sood, S Ansari… - International journal of …, 2023 - mdpi.com
Nonepithelial ovarian cancers (NEOC) are a group of rare malignancies, including germ cell
tumours (GCT) and sex cord-stromal tumours (SCST), along with small-cell carcinomas and …

Aberrations of DNA repair pathways in prostate cancer: A cornerstone of precision oncology

S Boussios, E Rassy, S Shah, E Ioannidou… - Expert opinion on …, 2021 - Taylor & Francis
Prostate cancer is the second most commonly diagnosed malignancy and the fifth most
frequent cause of cancerrelated death in males worldwide [1]. Although most cases of …