How I personalize fluid therapy in septic shock?
During septic shock, fluid therapy is aimed at increasing cardiac output and improving tissue
oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has …
oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has …
[HTML][HTML] The “CHEOPS” bundle for the management of Left Ventricular Diastolic Dysfunction in critically ill patients: an experts' opinion
F Sanfilippo, A Messina, S Scolletta, E Bignami… - … Critical Care & Pain …, 2023 - Elsevier
The impact of left ventricular (LV) diastolic dysfunction (DD) on the outcome of patients with
heart failure was established over three decades ago. Nevertheless, the relevance of LVDD …
heart failure was established over three decades ago. Nevertheless, the relevance of LVDD …
Reliability of pulse pressure and stroke volume variation in assessing fluid responsiveness in the operating room: a metanalysis and a metaregression
A Messina, M Caporale, L Calabrò, G Lionetti, D Bono… - Critical Care, 2023 - Springer
Background Pulse pressure and stroke volume variation (PPV and SVV) have been widely
used in surgical patients as predictors of fluid challenge (FC) response. Several factors may …
used in surgical patients as predictors of fluid challenge (FC) response. Several factors may …
Assessment of fluid responsiveness using pulse pressure variation, stroke volume variation, plethysmographic variability index, central venous pressure, and inferior …
Importance Maneuvers assessing fluid responsiveness before an intravascular volume
expansion may limit useless fluid administration, which in turn may improve outcomes …
expansion may limit useless fluid administration, which in turn may improve outcomes …
Testing preload responsiveness by the tidal volume challenge assessed by the photoplethysmographic perfusion index
C Bruscagnin, R Shi, D Rosalba, G Fouqué, J Hagry… - Critical Care, 2024 - Springer
Background To detect preload responsiveness in patients ventilated with a tidal volume (Vt)
at 6 mL/kg of predicted body weight (PBW), the Vt-challenge consists in increasing Vt from 6 …
at 6 mL/kg of predicted body weight (PBW), the Vt-challenge consists in increasing Vt from 6 …
Fluid boluses and infusions in the early phase of resuscitation from septic shock and sepsis-induced hypotension: a retrospective report and outcome analysis from a …
A Messina, M Albini, N Samuelli, A Brunati… - Annals of Intensive …, 2024 - Springer
Background Fluid administration is the first line treatment in intensive care unit (ICU) patients
with sepsis and septic shock. While fluid boluses administration can be titrated by predicting …
with sepsis and septic shock. While fluid boluses administration can be titrated by predicting …
The effect of passive leg raising test on intracranial pressure and cerebral autoregulation in brain injured patients: a physiological observational study
Background The use of the passive leg raising (PLR) is limited in acute brain injury (ABI)
patients with increased intracranial pressure (ICP) since the postural change of the head …
patients with increased intracranial pressure (ICP) since the postural change of the head …
Inspiratory effort impacts the accuracy of pulse pressure variations for fluid responsiveness prediction in mechanically ventilated patients with spontaneous breathing …
H Chen, M Liang, Y He, JL Teboul, Q Sun, J Xie… - Annals of Intensive …, 2023 - Springer
Background Pulse pressure variation (PPV) is unreliable in predicting fluid responsiveness
(FR) in patients receiving mechanical ventilation with spontaneous breathing activity …
(FR) in patients receiving mechanical ventilation with spontaneous breathing activity …
[HTML][HTML] Cardiac Output changes during renal replacement therapy: a Scoping Review
Introduction: Renal replacement therapy (RRT) is associated with hypotension. However, its
impact on cardiac output (CO) is less understood. We aimed to describe current knowledge …
impact on cardiac output (CO) is less understood. We aimed to describe current knowledge …
Conditional treatment effect analysis of two infusion rates for fluid challenges in critically Ill patients: a secondary analysis of balanced solution versus saline in …
Rationale: Optimal infusion rate for fluid challenges in critically ill patients is unknown. A
large clinical trial comparing two different infusion rates yielded neutral results. Conditional …
large clinical trial comparing two different infusion rates yielded neutral results. Conditional …