Reviewing the potential links between viral infections and TDP-43 proteinopathies

Z Rahic, E Buratti, S Cappelli - International Journal of Molecular …, 2023 - mdpi.com
Transactive response DNA binding protein 43 kDa (TDP-43) was discovered in 2001 as a
cellular factor capable to inhibit HIV-1 gene expression. Successively, it was brought to new …

Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review …

A Kahriman, J Bouley, TW Smith, DA Bosco… - Acta Neuropathologica …, 2021 - Springer
Traumatic brain injury (TBI) constitutes one of the strongest environmental risk factors for
several progressive neurodegenerative disorders of cognitive impairment and dementia that …

Traumatic brain injury induces TDP-43 mislocalization and neurodegenerative effects in tissue distal to the primary injury site in a non-transgenic mouse

GR Bjorklund, J Wong, D Brafman, R Bowser… - Acta neuropathologica …, 2023 - Springer
Traumatic brain injury (TBI) initiates tissue and cellular damage to the brain that is
immediately followed by secondary injury sequalae with delayed and continual damage …

Hippocampal-dependent cognitive dysfunction following repeated diffuse rotational brain injury in male and female mice

LB Tucker, AH Fu, JT McCabe - Journal of neurotrauma, 2021 - liebertpub.com
Cognitive dysfunction is a common, often long-term complaint following acquired traumatic
brain injury (TBI). Cognitive deficits suggest dysfunction in hippocampal circuits. The goal of …

[HTML][HTML] Single Versus Repetitive Traumatic Brain Injury: Current Knowledge on the Chronic Outcomes, Neuropathology and the Role of TDP-43 Proteinopathy

T Janković, K Pilipović - Experimental neurobiology, 2023 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is one of the most important causes of death and disability in
adults and thus an important public health problem. Following TBI, secondary …

Long-term effects of repetitive mild traumatic injury on the visual system in wild-type and TDP-43 transgenic mice

K Pilipović, J Rajič Bumber, P Dolenec… - International journal of …, 2021 - mdpi.com
Little is known about the impairments and pathological changes in the visual system in mild
brain trauma, especially repetitive mild traumatic brain injury (mTBI). The goal of this study …

[HTML][HTML] Repetitive Mild but Not Single Moderate Brain Trauma Is Associated with TAR DNA-Binding Protein 43 Mislocalization and Glial Activation in the Mouse …

T Janković, J Rajič Bumber, N Gržeta Krpan, P Dolenec… - Biomedicines, 2025 - mdpi.com
Background/Objectives: Traumatic brain injury (TBI) occurs after a sudden mechanical force
to the skull and represents a significant public health problem. Initial brain trauma triggers …

Neuroprotective Effects of Nanowired Delivery of Cerebrolysin with Mesenchymal Stem Cells and Monoclonal Antibodies to Neuronal Nitric Oxide Synthase in Brain …

HS Sharma, DF Muresanu, A Nozari… - … in Nanomedicine in …, 2023 - Springer
Concussive head injury (CHI) is one of the major risk factors in developing Alzheimer's
disease (AD) in military personnel at later stages of life. Breakdown of the blood–brain …

Differential expression patterns of TDP-43 in single moderate versus repetitive mild traumatic brain injury in mice

T Janković, P Dolenec, J Rajič Bumber… - International journal of …, 2021 - mdpi.com
Traumatic brain injury (TBI) is a disabling disorder and a major cause of death and disability
in the world. Both single and repetitive traumas affect the brain acutely but can also lead to …

Nanowired delivery of antibodies to tau and neuronal nitric oxide synthase together with cerebrolysin attenuates traumatic brain injury induced exacerbation of brain …

A Ozkizilcik, A Sharma, L Feng, DF Muresanu… - International Review of …, 2023 - Elsevier
Concussive head injury (CHI) is one of the major risk factors for developing Parkinson's
disease in later life of military personnel affecting lifetime functional and cognitive …