The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Mechanical ventilation has been used to support acutely ill patients for several decades. But
clinicians are aware that, despite the life-saving potential of this assistance, it has several …

One of the most challenging problems in critical care medicine is the management of
patients with the acute respiratory distress syndrome. Increasing evidence from …

Bronchopulmonary dysplasia (BPD)/chronic lung disease occurs primarily in very low birth
weight infants (VLBW) often without antecedent severe respiratory distress syndrome. The …

The onset of ventilator-induced lung injury (VILI) is linked to a number of possible
mechanisms. To isolate the possible role of alveolar epithelial deformation in the …

A comprehensive update to this preeminent and accessible text, this fifth edition of a
bestseller was developed as a response to man's attempts to climb unaided to higher …

The cause of chronic lung disease of early infancy, often called bronchopulmonary
dysplasia (BPD), remains unclear, partly because large-animal models that reliably …

Objectives: Many mechanically ventilated patients with acute respiratory distress syndrome
develop pulmonary fibrosis. Stresses induced by mechanical ventilation may explain the …

The pulmonary blood-gas barrier is an extraordinary bioengineering structure because of its
vast area but extreme thinness. Despite this, almost no attention has been given to its …

In vitro studies of the alveolar epithelial response to deformation require knowledge of the in
situ mechanical environment of these cells. Because of the presence of tissue folding and …