Tendon ruptures are a great burden in clinics. Finding a proper graft material as a substitute
for tendon repair is one of the main challenges in orthopaedics, for which the requirement of …

Bioreactors have the potential to advance the clinical application of cell-based therapies.
Cell expansion bioreactors have been used commercially for therapeutic applications; …

Objective: Acellular human tendons are a candidate scaffold for tissue engineering flexor
tendons of the hand. This study compared acellularization methods and their compatibility …

Musculoskeletal injuries that disrupt the structure and function of diarthrodial joints can
cause permanent biomechanical alterations and lead to a more severe, chronic condition …

Despite advances in understanding of the mechanical aspects of tendon management with
improved suture technique and early stress application with postoperative therapy, clinical …

Tendon is a connective tissue mainly composed of collagen fibers with peculiar mechanical
properties essential to functional movements. The increasing incidence of tendon traumatic …

Background: In mutilating hand injuries, tissue engineered tendon grafts may provide a
reconstructive solution. We have previously described a method to decellularize cadaveric …

Tendon injuries impose significant clinical burdens on healthcare systems worldwide. At
present, no therapeutic methods can cure tendon injuries in an ideal manner. With the …

Tendon healing is generally a time-consuming process and often leads to a functionally
altered reparative tissue. Using degradable scaffolds for tendon reconstruction still remains …

Background: Tissue-engineered flexor tendon grafts may allow reconstruction of severe
tendon losses. One critical factor is the optimization of cell proliferation and reseeding. Use …