Lipopolysccharide (LPS) is an integral component of the Pseudomonas aeruginosa cell
envelope, occupying the outer leaflet of the outer membrane in this Gram-negative …

Bacterial infections, with the most severe form being sepsis, can often not be treated
adequately leading to high morbidity and lethality of infected patients in critical care units. In …

Host defense peptides (HDPs) are part of the innate immune system and constitute a first
line of defense against invading pathogens. They possess antimicrobial activity against a …

The review is devoted to recent progress in the structural elucidation of the
lipopolysaccharide of the bacterium Pseudomonas aeruginosa, including O-antigen …

The focus of this review is the application of mass spectrometry to the structural
characterization of bacterial lipopolysaccharides (LPSs), also referred to as “endotoxins,” …

We describe an innovative use for the recently reported fast lipid analysis technique (FLAT)
that allows for the generation of MALDI tandem mass spectrometry data suitable for lipid A …

The possibility to rapidly identify bacteria is required in many different fields. Due to rapid
progress in the development of mass spectrometry devices during the last few years …

To determine whether growth of bacteria in biofilms triggers a specific immune response, we
compared cytokine induction in human monocytes and mouse macrophages by planktonic …

Lipopolysaccharides (LPS) are the main constituent of the outer bacterial membrane of
Gram-negative bacteria. Lipid-A is the structural region of LPS that interacts with the innate …

The lipid A domain of the endotoxic lipopolysaccharide layer of Gram-negative bacteria is
comprised of a diglucosamine backbone to which a variable number of variable length fatty …