Background: In this review article, a brief overview of novel metallotherapeutic agents (with
an emphasis on the complexes of essential biometals) promising for medical application is …

A First Course in Systems Biology is an introduction for advanced undergraduate and
graduate students to the growing field of systems biology. Its main focus is the development …

Ionic liquids (ILs) have been used as a kind of green solvents trying to preserve protein
drugs for many years. However, the protective mechanism of ILs on protein drugs is still …

Ionic liquids, as a kind of novel green solvents, have been widely applied to structural
stability study of protein due to their unique physicochemical properties. In this study, insulin …

离子液体作为一种新型绿色溶剂, 由于其独特的物理化学性质, 被广泛应用于蛋白质的稳定性
研究. 选用热敏性蛋白药物胰岛素作为研究对象, 采用分子动力学模拟方法 …

High Resolution Structure of the Manganese Derivative of Insulin† Page 1 † This article
belongs to the Special Issue devoted to the 85th anniversary of Croatica Chemica Acta …

Biopharmaceuticals are proteins with a crucial role in the treatment of many diseases.
However, these protein medicines are often thermally labile and therefore unsuitable for …

本文运用分子模拟和量子化学计算, 研究三种胰岛素聚集体的热稳定性以及锌(II)
离子配位作用对于这些聚集体生成反应的热力学影响. 分子模拟的研究结果表明 …

The dipole interaction model is a classical electromagnetic theory for calculating circular
dichroism (CD) resulting from the π-π* transitions of amides. The theoretical model …

采用微量热分析法并结合分子动力学模拟, 研究了不同双糖保护剂对胰岛素的保护效果.
结果表明, 通过区域选择性吸附, 双糖保护剂可以在胰岛素表面产生保护作用 …