Conventional 2D intestinal models cannot precisely recapitulate biomimetic features in vitro and thus are unsuitable for various pharmacokinetic applications, development of disease …
The barrier functions of the gastrointestinal tract rely in large part on a single layer of columnar intestinal epithelial cells. These epithelial cells are mediators of intestinal …
KA Wodzanowski, SE Cassel, CL Grimes… - Bioorganic & medicinal …, 2020 - Elsevier
Healthy function of the gut microenvironment is dependent on complex interactions between the bacteria of the microbiome, epithelial and immune (host) cells, and the surrounding …
It has become widely appreciated that mechanical forces are ever present between cells and their surroundings and that these forces provide a crucial set of cellular signals that can …