Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

Although a wealth of data have elucidated the structure and physiology of neuronal circuits,
we still only have a very limited understanding of how behavioral learning is implemented at …

GABA A receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …

Ion channels are membrane proteins expressed in almost all living cells. The sequencing of
the human genome has identified more than 400 putative ion channels, but only a fraction of …

The principal inhibitory neurotransmitter in the mammalian brain, γ-aminobutyric acid
(GABA), is thought to regulate memory processes by activating transient inhibitory …

GABAA receptors are molecular substrates for the regulation of vigilance, anxiety, muscle
tension, epileptogenic activity, and memory functions, and the enhancement of GABAA …

The diversity of GABAA receptor (GABAAR) subunits and the numerous configurations
during subunit assembly give rise to a variety of receptors with different functional properties …

Because of its control of spike-timing and oscillatory network activity, γ-aminobutyric acid
(GABA)-ergic inhibition is a key element in the central regulation of somatic and mental …

Publisher Summary This chapter describes the structure, pharmacology, and function of γ‐
aminobutyric acid type A (GABA A) receptor subtypes. GABA A receptors are the most …

α5 subunit containing GABA type A receptors (GABAARs) have long been an enigmatic
receptor subtype of interest due to their specific brain distribution, unusual surface …