A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Association of the epithelial–mesenchymal transition (EMT) with cisplatin resistance

M Ashrafizadeh, A Zarrabi, K Hushmandi… - International journal of …, 2020 - mdpi.com
Therapy resistance is a characteristic of cancer cells that significantly reduces the
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …

[HTML][HTML] Liquid biopsy in ovarian cancer using circulating tumor DNA and cells: Ready for prime time?

DB Asante, L Calapre, M Ziman, TM Meniawy, ES Gray - Cancer letters, 2020 - Elsevier
Liquid biopsies hold the potential to inform cancer patient prognosis and to guide treatment
decisions at the time when direct tumor biopsy may be impractical due to its invasive nature …

Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

Epithelial cell adhesion molecule: an anchor to isolate clinically relevant circulating tumor cells

In the last few decades, the epithelial cell adhesion molecule (EpCAM) has received
increased attention as the main membrane marker used in many enrichment technologies to …

Circulating tumour cells in the-omics era: how far are we from achieving the 'singularity'?

TH Visal, P den Hollander, M Cristofanilli… - British journal of …, 2022 - nature.com
Over the past decade, cancer diagnosis has expanded to include liquid biopsies in addition
to tissue biopsies. Liquid biopsies can result in earlier and more accurate diagnosis and …

Survival mechanisms and influence factors of circulating tumor cells

WC Wang, XF Zhang, J Peng, XF Li… - BioMed research …, 2018 - Wiley Online Library
Circulating tumor cells (CTCs) are cancer cells shed from either the primary tumor or its
metastases that circulate in the peripheral blood. The CTCs are regarded as the source of …

Liquid biopsy: one cell at a time

SB Lim, W Di Lee, J Vasudevan, WT Lim… - NPJ precision …, 2019 - nature.com
As an alternative target to surgically resected tissue specimens, liquid biopsy has gained
much attention over the past decade. Of the various circulating biomarkers, circulating tumor …

High-efficiency isolation and rapid identification of heterogeneous circulating tumor cells (CTCs) using dual-antibody-modified fluorescent-magnetic nanoparticles

Z Wang, N Sun, H Liu, C Chen, P Ding… - … applied materials & …, 2019 - ACS Publications
Extreme rarity and inherent heterogeneity of circulating tumor cells (CTCs) result in a
tremendous challenge for the CTC isolation from patient blood samples with high efficiency …

Magnetically driven microfluidics for isolation of circulating tumor cells

L Luo, Y He - Cancer Medicine, 2020 - Wiley Online Library
Circulating tumor cells (CTCs) largely contribute to cancer metastasis and show potential
prognostic significance in cancer isolation and detection. Miniaturization has progressed …