Mitochondria: a target for bacteria

E Lobet, JJ Letesson, T Arnould - Biochemical pharmacology, 2015 - Elsevier
Eukaryotic cells developed strategies to detect and eradicate infections. The innate immune
system, which is the first line of defence against invading pathogens, relies on the …

Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury

K Chen, Z Xu, Y Liu, Z Wang, Y Li, X Xu… - Science translational …, 2017 - science.org
Limb remote ischemic preconditioning (RIPC) is an effective means of protection against
ischemia/reperfusion (IR)–induced injury to multiple organs. Many studies are focused on …

The role of CD38 in Fcγ receptor (FcγR)-mediated phagocytosis in murine macrophages

J Kang, KH Park, JJ Kim, EK Jo, MK Han… - Journal of Biological …, 2012 - ASBMB
Phagocytosis is a crucial event in the immune system that allows cells to engulf and
eliminate pathogens. This is mediated through the action of immunoglobulin (IgG) …

Mitochondrial uncoupling protein 2 protects splenocytes from oxidative stress-induced apoptosis during pathogen activation

T Cao, Y Dong, R Tang, J Chen, CY Zhang, K Zen - Cellular immunology, 2013 - Elsevier
Accumulating evidences suggested that mitochondrial uncoupling protein 2 (UCP2) is
involved in host defense in parasite infection, inflammation, and autoimmune responses …

[HTML][HTML] Frequency of UCP2 45-bp Ins/Del polymorphism in Saudi population from Jazan area and its association with autoimmune hypothyroidism UCP2 45-bp Ins …

YA Kaabi, AS Mansor, AS Alfagih… - … Journal of Health …, 2020 - ncbi.nlm.nih.gov
Objectives: Autoimmune hypothyroidism (AHT) is a common endocrine disorder. Although
the exact cause of AHT is not yet understood, genetic factors may play a major role …

Uncoupling protein-2 deficient mice are not protected against warm ischemia/reperfusion injury of the liver

K Le Minh, A Berger, C Eipel, A Kuhla, T Minor… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Uncoupling protein-2 (UCP2) might play an important role in mediating
ischemia/reperfusion (I/R) injury due to its function in uncoupling of oxidative …

Novel Roles for IFNß and Uncoupling Protein 2 in Regulating Macrophage Function During the Resolution of Inflammation

J Saadi - 2016 - search.proquest.com
The resolution of inflammation is an active and tightly regulated process. Dysregulation of
this process leads to persistent, uncontrolled, and chronic inflammatory diseases. Monocyte …

[引用][C] 解偶联蛋白-2 及缺氧诱导因子-1 在肿瘤细胞中表达的意义

戴纪刚, 汤兴平, 闵家新, 余祖滨, 张在永 - 现代医药卫生, 2012